1-Bromo-2,4-difluorobenzene

Basic Information

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CAS Number

348-57-2

Molecular Formula

C6H3BrF2

Molecular Weight

192.99 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

−4 °C

Boiling Point

146°C

Refractive Index

n20/D 1.505(lit.)

SMILES

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C1=CC(=C(C=C1F)F)Br

InChI

InChI=1S/C6H3BrF2/c7-5-2-1-4(8)3-6(5)9/h1-3H

InChIKey

MGHBDQZXPCTTIH-UHFFFAOYSA-N

LogP

2.7273000000000005

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

97.1

Safety Information

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GHS Hazard Pictograms

H226

H315

H319

H335

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 3 Class 3

Synonyms & References

English

NS00005837
1-bromo-2,4-difluorobenzene;2,4-Difluorobromobenzene
AKOS000179355
EINECS 206-479-4
DTXSID40188336
CS-W010697
InChI=1/C6H3BrF2/c7-5-2-1-4(8)3-6(5)9/h1-3
D1909
2,4-Difluoro-1-bromobenzene
Benzene, 1-bromo-2,4-difluoro-
PS-10243
SCHEMBL14413
348-57-2
BROMO-2,4-DIFLUOROBENZENE
EN300-65437
FT-0631998
1-Bromo-2,4-difluoro-benzene
2,4-Difluorobromobenzene
EC 206-479-4
AM928
1-Bromo-2,4-difluorobenzene, 98%
MFCD00000330
1-bromo-2,4-diflurobenzene
W-106704
2,4-difluoro-bromobenzene
AC-10627
A6515
1-Bromo-2,4-difluorobenzene
3-bromo-2,6-difluorobenzene
1-Bromo-2,4-difluoro
1-bromo-2,4-difluoro-benzene

MDL Number

MFCD00000330

Customs Code

29036990

FAQ

What is 1-Bromo-2,4-difluorobenzene (CAS: 348-57-2)?

1-Bromo-2,4-difluorobenzene (CAS: 348-57-2) is an aromatic organic compound with the chemical formula C6H3BrF2. It features a benzene ring substituted with bromo and difluoro groups at positions 1, 2, and 4. This compound is typically a colorless to pale yellow liquid, known for its stability and reactivity in chemical synthesis. Its halogenated structure makes it a valuable precursor in various industrial and research applications.

What are the main uses of 1-Bromo-2,4-difluorobenzene (CAS: 348-57-2)?

1-Bromo-2,4-difluorobenzene (CAS: 348-57-2) is primarily used in pharmaceuticals as an intermediate for synthesizing drugs with enhanced bioavailability. It also finds applications in agrochemicals, materials science, and organic research due to its versatile functional groups. Its unique chemical properties make it suitable for creating fluorinated and brominated compounds in industrial processes.

Is 1-Bromo-2,4-difluorobenzene (CAS: 348-57-2) safe?

1-Bromo-2,4-difluorobenzene (CAS: 348-57-2) requires careful handling due to potential toxicity. It may cause irritation to the skin, eyes, and respiratory system, and is harmful if ingested. Safety measures include using personal protective equipment (PPE) like gloves, goggles, and a fume hood. It is classified as a hazardous chemical under OSHA and EPA guidelines, necessitating adherence to proper storage and disposal protocols.

How should 1-Bromo-2,4-difluorobenzene (CAS: 348-57-2) be stored?

1-Bromo-2,4-difluorobenzene (CAS: 348-57-2) should be stored in a cool, dry, and well-ventilated area, away from light and incompatible materials. Keep it in a sealed, airtight container made of glass or stainless steel to prevent contamination. Ensure storage conditions maintain stability, and follow safety standards to avoid exposure risks. Always store it in a designated chemical storage cabinet for hazardous substances.