Ethyl 5-fluoro-1H-indole-2-carboxylate

Basic Information

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CAS Number

348-36-7

Molecular Formula

C11H10FNO2

Molecular Weight

207.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

147.0 to 151.0 deg-C

Boiling Point

312°Cat760mmHg

Density

1.491

Flash Point

142.5°C

Refractive Index

1.6

SMILES

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CCOC(=O)C1=CC2=C(N1)C=CC(=C2)F

InChI

InChI=1S/C11H10FNO2/c1-2-15-11(14)10-6-7-5-8(12)3-4-9(7)13-10/h3-6,13H,2H2,1H3

InChIKey

VIKOQTQMWBKMNA-UHFFFAOYSA-N

LogP

2.4837

Topological Polar Surface Area

42.09 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

247

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

ethyl5-fluoro-indole-2-carboxylate
AKOS001476058
SCHEMBL830789
348-36-7
Ethyl 5-fluoroindole-2-carboxylate
MFCD00152076
E1035
ethyl 5-fluoro-1H-indole-2--carboxylate
ethyl 5-fluoro-indole-2-carboxylate
5-Fluoroindole-2-carboxylic acid ethyl ester
AB01332088-02
A822425
VIKOQTQMWBKMNA-UHFFFAOYSA-N
5-fluoro-1H-indole-2-carboxylic acid, ethyl ester
5-F-ICA-OEt
Ethyl 5-fluoroindole-2-carboxylate, 96%
ethyl 5-fluoro-1H-indole-2-carboxylate
1H-Indole-2-carboxylic acid, 5-fluoro-, ethyl ester
SB14860
F-5300
SY050136
Z307629108
Maybridge1_006190
CS-W015274
EN300-112766
FS-1259
HMS559B08
2-carbethoxy-5-fluoroindole
CCG-237182
NCGC00341411-01
SC2241

MDL Number

MFCD00152076

Customs Code

2933990090

FAQ

What is Ethyl 5-fluoro-1H-indole-2-carboxylate (CAS: 348-36-7)?

Ethyl 5-fluoro-1H-indole-2-carboxylate (CAS: 348-36-7) is an organic compound with the molecular formula C10H9FN2O2. It is a derivative of indole with a fluoro substituent and an ethyl ester group. This compound is characterized by its stability in various chemical reactions and is often used in organic synthesis and pharmaceutical research.

What are the main uses of Ethyl 5-fluoro-1H-indole-2-carboxylate (CAS: 348-36-7)?

Ethyl 5-fluoro-1H-indole-2-carboxylate (CAS: 348-36-7) is primarily used in the synthesis of indole-based pharmaceuticals and agrochemicals. It serves as an intermediate in the production of compounds with biological activities, such as selective serotonin reuptake inhibitors (SSRIs) and other drugs targeting various diseases.

Is Ethyl 5-fluoro-1H-indole-2-carboxylate (CAS: 348-36-7) safe?

Ethyl 5-fluoro-1H-indole-2-carboxylate (CAS: 348-36-7) is generally considered safe for laboratory use under appropriate handling conditions. However, it is important to follow safety guidelines, including the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat, to prevent skin contact and inhalation. Storage and disposal should be done in accordance with local regulations.

How should Ethyl 5-fluoro-1H-indole-2-carboxylate (CAS: 348-36-7) be stored?

Ethyl 5-fluoro-1H-indole-2-carboxylate (CAS: 348-36-7) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation. Proper storage conditions are essential to maintain its chemical integrity and ensure safe handling during use.