(4R)-1,3-Thiazolidine-4-carboxylic acid

Basic Information

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CAS Number

34592-47-7

Molecular Formula

C4H7NO2S

Molecular Weight

133.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

190-200 °C (dec.)

Water Solubility

28.5 g/L (20 ºC)

Refractive Index

-200 ° (C=1, 1mol/L NaOH)

Specific Rotation

-101 º (c=1, 1N HCl)

SMILES

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O=C([C@H]1NCSC1)O

InChI

InChI=1S/C4H7NO2S/c6-4(7)3-1-8-2-5-3/h3,5H,1-2H2,(H,6,7)/t3-/m0/s1

InChIKey

DZLNHFMRPBPULJ-VKHMYHEASA-N

LogP

-0.2665

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

101

Safety Information

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GHS Hazard Pictograms

H301

H312

H315

H319

H332

H335

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Stability

Stable. Incompatible with strong oxidizing agents.

Synonyms & References

English

(R)-Thiazolidine-4-carboxylic acid
thiazolidinecarboxylicacid
(R)-(-)-THIAZOLIDINE-4-CARBOXYLIC ACID
THIOPROLINE
THIAPROLINE
L-THIAPROLINE
L(-)-THIAZOLIDINE-4-CARBOXYLIC ACID
L-THIAZOLIDINE-4-CARBOXYLIC ACID
L-Thioproline
(R)-1,3-Thiazolidine-4-carboxylic acid
(S)-thiazolidine-4-carboxylic acid
L-4-Thiazolidinecarboxylic acid
(4R)-1,3-thiazolidine-4-carboxylic acid
(R)-(-)-thiazolidine-4
(R)-4-Thiazolidinecarboxylic acid
H-THZ-OH
L-THC
L-Thiazolidine-4-car
L-thiazoline-4-carboxylic acid
(R)-thiazolidine-4-carboxylic acid

MDL Number

MFCD00005212

Customs Code

29341000

FAQ

What is (4R)-1,3-Thiazolidine-4-carboxylic acid (CAS: 34592-47-7)?

(4R)-1,3-Thiazolidine-4-carboxylic acid (CAS: 34592-47-7) is a thiazolidine derivative with the chemical formula C4H6N2O2S. It is a white crystalline solid with a characteristic odor, commonly used in organic synthesis. This compound exhibits moderate solubility in water and is known for its stability under normal conditions, making it a valuable intermediate in pharmaceutical and industrial applications.

What are the main uses of (4R)-1,3-Thiazolidine-4-carboxylic acid (CAS: 34592-47-7)?

(4R)-1,3-Thiazolidine-4-carboxylic acid (CAS: 34592-47-7) is primarily used as a pharmaceutical intermediate for drug development, particularly in antidiabetic and antiviral therapies. It also finds applications in the synthesis of chiral compounds and as a building block in organic chemistry research. Its utility extends to industrial processes involving functional group modification and compound stabilization.

Is (4R)-1,3-Thiazolidine-4-carboxylic acid (CAS: 34592-47-7) safe?

The safety of (4R)-1,3-Thiazolidine-4-carboxylic acid (CAS: 34592-47-7) depends on proper handling. While it is generally considered safe in controlled environments, it may cause irritation to the skin, eyes, or呼吸道 if mishandled. Always follow safety standards, use protective gear like gloves and goggles, and ensure adequate ventilation when working with this compound to minimize risks.

How should (4R)-1,3-Thiazolidine-4-carboxylic acid (CAS: 34592-47-7) be stored?

(4R)-1,3-Thiazolidine-4-carboxylic acid (CAS: 34592-47-7) should be stored in a sealed, airtight container in a cool, dry place (ideally 2-8°C) to maintain stability. Protection from light and moisture is essential to prevent degradation. Ensure storage in a well-ventilated area and follow guidelines to avoid exposure to incompatible substances, preserving its chemical integrity and safety.