1-(Chloromethyl)-2-fluorobenzene

Basic Information

View in Editor

CAS Number

345-35-7

Molecular Formula

C7H6ClF

Molecular Weight

144.58 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

175°C

Solubility

0.416g/l insoluble

Refractive Index

n20/D 1.514(lit.)

SMILES

View in Editor

C1=CC=C(C(=C1)CCl)F

InChI

InChI=1S/C7H6ClF/c8-5-6-3-1-2-4-7(6)9/h1-4H,5H2

InChIKey

MOBRMRJUKNQBMY-UHFFFAOYSA-N

LogP

2.5645000000000007

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

Safety Information

View Safety Information

GHS Hazard Pictograms

H226

H314

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 (3) Class 8 (3)

Sensitiveness

Lachrymatory

Synonyms & References

English

345-35-7
AM81464
AKOS000119256
EINECS 206-460-0
1-(Chloromethyl)-2-fluorobenzene
MFCD00000892
.alpha.-Chloro-o-fluorotoluene
o-fluorobenzylchloride
O-FLUOROBENZYL CHLORIDE
InChI=1/C7H6ClF/c8-5-6-3-1-2-4-7(6)9/h1-4H,5H2
DTXSID9059838
NSC-88295
NSC 88295
2-Fluorobenzyl chloride
1-(chloromethyl)-2-fluoro-benzen
F0211
FT-0612421
MOBRMRJUKNQBMY-UHFFFAOYSA-
alpha-Chloro-2-fluorotoluene
1-Chloromethyl-2-fluorobenzene
AC-10797
Toluene, .alpha.-chloro-o-fluoro-
NS00041566
A25292
1-Chloromethyl-2-fluoro-benzene
alpha-Chloro-o-fluorotoluene
NSC88295
2-fluoro-benzyl chloride
2-fluorophenylmethyl chloride
2-flourobenzyl chloride
Benzene, 1-(chloromethyl)-2-fluoro-

MDL Number

MFCD00000892

Customs Code

29036990

FAQ

What is 1-(Chloromethyl)-2-fluorobenzene (CAS: 345-35-7)?

1-(Chloromethyl)-2-fluorobenzene (CAS: 345-35-7) is an aromatic organic compound with the chemical formula C7H6ClF. It features a benzene ring substituted with a chloromethyl group at the 1-position and a fluorine atom at the 2-position. This compound is liquid at room temperature, has a low boiling point, and is soluble in organic solvents. Its unique structure makes it valuable in chemical synthesis.

What are the main uses of 1-(Chloromethyl)-2-fluorobenzene (CAS: 345-35-7)?

1-(Chloromethyl)-2-fluorobenzene (CAS: 345-35-7) is primarily used as an intermediate in pharmaceutical and agrochemical synthesis. It also finds applications in organic research for developing new materials and derivatives. Due to its reactivity, it is utilized in industrial processes to create fluorinated compounds and functionalized aromatic molecules.

Is 1-(Chloromethyl)-2-fluorobenzene (CAS: 345-35-7) safe?

1-(Chloromethyl)-2-fluorobenzene (CAS: 345-35-7) requires careful handling due to potential toxicity. It may cause skin and eye irritation, and inhalation could lead to respiratory issues. Safety standards recommend using appropriate PPE, working in a well-ventilated area, and adhering to OSHA guidelines. Proper storage is essential to minimize risks.

How should 1-(Chloromethyl)-2-fluorobenzene (CAS: 345-35-7) be stored?

1-(Chloromethyl)-2-fluorobenzene (CAS: 345-35-7) should be stored in a cool, dry, and dark place, ideally at 2-8°C. Keep it in a sealed container to prevent exposure to air and moisture. Avoid contact with incompatible substances and ensure good ventilation. Store away from heat sources and keep it in a fume hood for safety.