2,5-Dibromo-4-methylpyridine

Basic Information

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CAS Number

3430-26-0

Molecular Formula

C6H5Br2N

Molecular Weight

250.92 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

38.0 to 42.0 deg-C

Boiling Point

181.5°C (rough estimate)

Flash Point

112.7℃

Refractive Index

1.6300 (estimate)

SMILES

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CC1=CC(=NC=C1Br)Br

InChI

InChI=1S/C6H5Br2N/c1-4-2-6(8)9-3-5(4)7/h2-3H,1H3

InChIKey

WWJLJUAHQHXDGM-UHFFFAOYSA-N

LogP

2.91502

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

97.1

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

SCHEMBL151857
A6040
CS-W010214
Pyridine, 2,5-dibromo-4-methyl-
AB05276
2,5-Dibromo-4-methyl-pyridine
2,5-Dibromo-4-Methyl Pyridine
BCP22208
PS-7470
D4058
WWJLJUAHQHXDGM-UHFFFAOYSA-N
MFCD00234955
2,5-Dibromo-4-methyl-pyridine;2,5-Dibromo-4-picoline
2,5-Dibromo-4-methylpyridine, 97%
2,5-Dibromo-4-methylpyridine
3430-26-0
FT-0610274
RB1048
HY-W009498
AKOS002664320
DTXSID70370308
Z1269154884
AC-1549
Q-101242
2,5-Dibromo-4-picoline
EN300-98170
2.5-Dibromo-4-methylpyridine
2,5-dibromo-4-methypyridine
AM62706
2,3-Dibromo-4-methylpyridine
2.5-dibromo-4-methylpyridine

MDL Number

MFCD00234955

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2,5-Dibromo-4-methylpyridine (CAS: 3430-26-0)?

2,5-Dibromo-4-methylpyridine (CAS: 3430-26-0) is a crystalline solid with a molecular weight of approximately 263.05 g/mol. It has a low water solubility and good solubility in common organic solvents like ethanol and acetone. This compound is known for its reactivity towards nucleophiles and electrophiles, making it useful in various synthetic transformations. It exhibits good stability at room temperature but should be stored in a cool, dry place away from direct sunlight.

How is 2,5-Dibromo-4-methylpyridine (CAS: 3430-26-0) typically synthesized?

2,5-Dibromo-4-methylpyridine (CAS: 3430-26-0) is commonly synthesized through the bromination of 4-methylpyridine with bromine in the presence of a base like sodium hydroxide. This reaction is typically carried out in aprotic solvents such as chloroform or dichloromethane. The yield and selectivity can be improved by optimizing the reaction conditions, such as temperature and solvent choice. The reaction is exothermic and should be monitored carefully to prevent overheating.

What industries use 2,5-Dibromo-4-methylpyridine (CAS: 3430-26-0)?

2,5-Dibromo-4-methylpyridine (CAS: 3430-26-0) is used in various industries. In the pharmaceutical industry, it serves as a precursor for the synthesis of certain drugs. It is also utilized in the polymer industry for the development of novel materials. Additionally, this compound has applications in the production of sensors and semiconductors, where its unique chemical properties make it a valuable reagent in these fields.

What precautions should be taken when handling 2,5-Dibromo-4-methylpyridine (CAS: 3430-26-0)?

When handling 2,5-Dibromo-4-methylpyridine (CAS: 3430-26-0), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and laboratory coats. This compound should be handled in a well-ventilated area or a fume hood due to its potential for vapor release. In the event of a spill, it should be carefully cleaned up using appropriate spill response procedures. It is also advisable to refer to the safety data sheet (SDS) for detailed information on handling and emergency response.