2-Methyl-3-pyridinamine

Basic Information

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CAS Number

3430-10-2

Molecular Formula

C6H8N2

Molecular Weight

108.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

114.0 to 118.0 deg-C

Boiling Point

236.8 ºC at 760 mmHg

Density

1.0680

Flash Point

120.1 ºC

SMILES

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CC1=C(C=CC=N1)N

InChI

InChI=1S/C6H8N2/c1-5-6(7)3-2-4-8-5/h2-4H,7H2,1H3

InChIKey

ZSFPJJJRNUZCEV-UHFFFAOYSA-N

LogP

0.9722199999999999

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

72.9

Safety Information

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GHS Hazard Pictograms

H302

H315

H318

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

3-Amino-2-methylpyridine
2-methyl-3-pyridinylamine
3-Amino-2-picoline
3-AMINOPICOLINE
3-Amino-2-methylpyridine (3-Amino-2-picoline)
3430-10-2
BP-10885
EN300-84026
SY003689
3-amino-2-methyl-pyridine
3-Pyridinamine, 2-methyl-
FT-0634850
3-Amino-2-methylpyridine, 97%
2-Methyl-3-Amino Pyridine
2-methylpyridin-3-amine
2-methyl-3-aminopyridine
MFCD03788195
2-methyl-pyridin-3-ylamine
2-methylpyridine-3-amine
AKOS005259077
W-204273
2-Methyl-3-pyridinamine
AM20051091
AC-1033
DTXSID40341368
PB33695
2-methylpyridin-3-amine;3-Amino-2-picolin
2-Methyl-3-pyridinamine #
PS-9286
SCHEMBL268392
(2-methyl-pyridin-3-yl)-amine

MDL Number

MFCD03788195

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Methyl-3-pyridinamine (CAS: 3430-10-2)?

2-Methyl-3-pyridinamine (CAS: 3430-10-2) is a crystalline solid at room temperature. It has a molecular weight of approximately 131.11 g/mol and is soluble in organic solvents like ethanol and acetone. It shows basic properties and is reactive towards acidic conditions. It can be used in synthetic routes due to its amine functionality.

How is 2-Methyl-3-pyridinamine (CAS: 3430-10-2) typically synthesized?

2-Methyl-3-pyridinamine (CAS: 3430-10-2) is commonly synthesized via the amidation of 2-methyl-3-pyridone with ammonia or amines. The reaction is typically carried out under basic conditions using a catalyst like sodium hydroxide. The yield is usually around 85-90%, and the method is known for its high selectivity.

What industries use 2-Methyl-3-pyridinamine (CAS: 3430-10-2)?

2-Methyl-3-pyridinamine (CAS: 3430-10-2) is used in various industries. It is particularly important in the pharmaceutical sector for the synthesis of certain drug candidates. It also finds applications in polymer chemistry and as a precursor in chemical sensors and semiconductors.

What precautions should be taken when handling 2-Methyl-3-pyridinamine (CAS: 3430-10-2)?

When handling 2-Methyl-3-pyridinamine (CAS: 3430-10-2), it is essential to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be managed carefully, and the Material Safety Data Sheet (MSDS) should be consulted for detailed emergency procedures.