Diphenyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate | CAS No. 342631-41-8

Diphenyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate

Basic Information

CAS Number

342631-41-8

Molecular Formula

C21H22N5O4P

Molecular Weight

439.41 g/mol

AD

Basic Physical Properties

C[C@H](Cn1cnc2c1ncnc2N)OCP(=O)(Oc3ccccc3)Oc4ccccc4

InChI

InChI=1S/C21H22N5O4P/c1-16(12-26-14-25-19-20(22)23-13-24-21(19)26)28-15-31(27,29-17-8-4-2-5-9-17)30-18-10-6-3-7-11-18/h2-11,13-14,16H,12,15H2,1H3,(H2,22,23,24)/t16-/m1/s1

InChIKey

XWTDSRIRFPGRAW-MRXNPFEDSA-N

LogP

4.122200000000002

Topological Polar Surface Area

114.38000000000002 Ų

Hydrogen Bond Donor/Acceptor

2 / 9

Synonyms & References

English

  • Tenofovir Alafenamide Impurity 1
  • diphenyl (R)-(((1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate

FAQ

What regulatory guidelines apply to Diphenyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate (CAS: 342631-41-8)?

Diphenyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate (CAS: 342631-41-8) is subject to regulatory guidelines under GHS (Globally Harmonized System of Classification and Labelling of Chemicals) for hazard communication. It may also be covered under REACH regulations in the EU, which require registration, evaluation, authorization, and restriction of chemicals. For specific FDA and EPA requirements, detailed handling, storage, and disposal guidelines should be adhered to as per the current regulations.

Are there alternatives to Diphenyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate (CAS: 342631-41-8) in synthesis?

There are a few alternatives to Diphenyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate (CAS: 342631-41-8) in synthesis. Common alternatives include other purine derivatives or phosphonates with similar functional groups. These alternatives can offer similar properties or improved synthetic efficiency and yield. Consulting with a chemist or查阅相关文献可以找到合适的替代品。

What is the market or research trend for Diphenyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate (CAS: 342631-41-8)?

The market for Diphenyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate (CAS: 342631-41-8) is currently growing due to its applications in medicinal chemistry and drug development. Research trends are focusing on optimizing its synthesis and exploring its potential as a therapeutic agent. Increased interest in purine-based compounds for treating various diseases is driving this trend.

How should waste containing Diphenyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate (CAS: 342631-41-8) be handled?

Waste containing Diphenyl ({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)phosphonate (CAS: 342631-41-8) should be collected in appropriate containers and stored separately. Incineration or professional waste disposal services are recommended. Ensure all environmental protection precautions are taken to prevent contamination. Consult local regulations for specific disposal requirements.

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