2-Methyl-2H-indazole-3-carbaldehyde

Basic Information

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CAS Number

34252-54-5

Molecular Formula

C9H8N2O

Molecular Weight

160.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

75-77

SMILES

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CN1C(=C2C=CC=CC2=N1)C=O

InChI

InChI=1S/C9H8N2O/c1-11-9(6-12)7-4-2-3-5-8(7)10-11/h2-6H,1H3

InChIKey

SMWLSZQHLMZHHV-UHFFFAOYSA-N

LogP

1.3858

Topological Polar Surface Area

34.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

183

Synonyms & References

English

J-509929
AS-31439
AKOS006346475
DTXSID60355907
SCHEMBL4360026
FT-0760828
2-methylindazole-3-carbaldehyde
EN300-1725325
34252-54-5
2-methyl-2H-indazole-3-carbaldehyde
CS-0101167
Z1201620676
AM803732
A875053
2-Methyl-2H-indazole-3-carboxaldehyde
MFCD00839530
2-methyl-3-formylindazole
2H-Indazole-3-carboxaldehyde,2-methyl-
2-Methyl-2H-indazole-3-carbaldehyde
2-Methyl-2H-indazol-3-carboxaldehyd
2-Methyl-3-formylindazol

MDL Number

MFCD00839530

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Methyl-2H-indazole-3-carbaldehyde (CAS: 34252-54-5)?

2-Methyl-2H-indazole-3-carbaldehyde (CAS: 34252-54-5) is a crystalline solid with a molecular weight of approximately 174.2 g/mol. It is slightly soluble in water but highly soluble in organic solvents such as ethanol and acetone. The compound is highly reactive, particularly towards nucleophiles and electrophiles, making it useful in various synthetic applications.

How is 2-Methyl-2H-indazole-3-carbaldehyde (CAS: 34252-54-5) typically synthesized?

2-Methyl-2H-indazole-3-carbaldehyde (CAS: 34252-54-5) can be synthesized via the Aldol condensation of 2-methylindole with an appropriate aldehyde in the presence of a base. This method provides a yield of up to 85%, and the reaction is typically catalyzed by a strong base such as sodium hydroxide.

What industries use 2-Methyl-2H-indazole-3-carbaldehyde (CAS: 34252-54-5)?

2-Methyl-2H-indazole-3-carbaldehyde (CAS: 34252-54-5) is used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the production of polymers, sensors, and as a precursor in semiconductor manufacturing, due to its unique chemical properties that facilitate various chemical reactions.

What precautions should be taken when handling 2-Methyl-2H-indazole-3-carbaldehyde (CAS: 34252-54-5)?

When handling 2-Methyl-2H-indazole-3-carbaldehyde (CAS: 34252-54-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate safety protocols, and the Material Safety Data Sheet (MSDS) should be consulted for detailed handling and emergency procedures.