(4R)-1-Acetyl-4-hydroxy-L-proline

Basic Information

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CAS Number

33996-33-7

Molecular Formula

C7H11NO4

Molecular Weight

173.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

132-133 °C (dec.)

Boiling Point

442.1℃ at 760 mmHg

Flash Point

221.2℃

Refractive Index

1.4490 (estimate)

Specific Rotation

-119 º (c=4 in H2O)

SMILES

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CC(=O)N1C[C@H](O)C[C@H]1C(=O)O

InChI

InChI=1S/C7H11NO4/c1-4(9)8-3-5(10)2-6(8)7(11)12/h5-6,10H,2-3H2,1H3,(H,11,12)/t5-,6+/m1/s1

InChIKey

BAPRUDZDYCKSOQ-RITPCOANSA-N

LogP

-0.9473

Topological Polar Surface Area

77.84 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

216

Safety Information

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GHS Hazard Pictograms

H318

Hazard Statement

H318 Causes serious eye damage
Serious eye damage/eye irritation

Synonyms & References

English

(2S,4R)-1-Acetyl-4-hydroxypyrrolidine-2-carboxylic acid
trans-1-Acetyl-4-hydroxy-L-proline
N-Acetyl-trans-4-hydroxy-L-proline
N-Acetylhydroxyproline
N-Acetyl-4-hydroxyproline
(R)-N-Acetyl-4-hydroxy-L-proline
1-Acetyl-4-hydroxy-pyrrolidine-2-carboxylic acid
AC-HYDROXYPROLINE
Ac-Hyp-OH
Ac-L-Hyp-OH
Ac-O-Hyp-OH
ML 161
N-Acetyl-L-4-hydroxyproline
N-ACETYL-L-HYDROXYPROLINE
Oxaceprol
(2S,4R)-1-acetyl-4-hydroxy-2-pyrrolidinecarboxylic acid
(2S,4R)-N-acetyl-4-hydroxyproline
1-acetyl-trans-4-hydroxy-L-proline
AHP-200
CO-61
Hyp4001Ac-Hyp-Oh
Jonctum
N-AC-L-HYP
trans-l-prolin
L-Proline, 1-acetyl-4-hydroxy-, (4R)-
Oxaceprol [INN]
Q0XV76B96L
Oxaceprol (INN)
DSSTox_RID_81589
DSSTox_CID_26410
DSSTox_GSID_46410

MDL Number

MFCD00037339

Customs Code

2933990090

FAQ

What is (4R)-1-Acetyl-4-hydroxy-L-proline (CAS: 33996-33-7)?

(4R)-1-Acetyl-4-hydroxy-L-proline, with the CAS number 33996-33-7, is a derivative of L-proline. It has the chemical formula C7H13NO4 and is known for its unique stereochemical configuration. This compound is characterized by its acetyl and hydroxy groups attached to the proline ring, contributing to its structural complexity and potential functional properties in various applications.

What are the main uses of (4R)-1-Acetyl-4-hydroxy-L-proline (CAS: 33996-33-7)?

(4R)-1-Acetyl-4-hydroxy-L-proline (CAS: 33996-33-7) is primarily used in pharmaceutical research for the development of drugs targeting metabolic disorders. It also finds applications in biochemical studies and as a building block for synthesizing other complex molecules. Its unique structure makes it relevant in drug design and chemical synthesis processes.

Is (4R)-1-Acetyl-4-hydroxy-L-proline (CAS: 33996-33-7) safe?

(4R)-1-Acetyl-4-hydroxy-L-proline (CAS: 33996-33-7) is generally considered safe when handled properly. However, as with any chemical, it should be used with caution, and appropriate safety measures such as gloves and ventilation should be taken. Safety data sheets (SDS) should be consulted for detailed handling and exposure guidelines.

How should (4R)-1-Acetyl-4-hydroxy-L-proline (CAS: 33996-33-7) be stored?

(4R)-1-Acetyl-4-hydroxy-L-proline (CAS: 33996-33-7) should be stored in a cool, dry, and dark place, away from moisture and air. It is typically kept in a sealed container at a temperature below 25°C to maintain its stability. Avoid exposure to light and ensure proper storage conditions to prevent degradation.