(6bS,9aR,12S)-12-Fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one

Basic Information

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CAS Number

3385-03-3

Molecular Formula

C24H31FO6

Molecular Weight

434.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

237-240°C (dec.)

Boiling Point

581.8ºC at 760mmHg

Flash Point

305.7ºC

SMILES

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CC1(OC2CC3C4CC(C5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C)F)C

InChI

InChI=1S/C24H31FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h5-7,13-14,16-17,19-20,26,28H,8-11H2,1-4H3/t13?,14?,16-,17?,19+,20?,22?,23?,24+/m0/s1

InChIKey

XSFJVAJPIHIPKU-CCRGDLLISA-N

LogP

2.2747000000000006

Topological Polar Surface Area

93.06000000000002 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

910

Safety Information

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GHS Hazard Pictograms

H300

Hazard Statement

H300 Fatal if swallowed
Acute toxicity, oral

Synonyms & References

English

SCHEMBL4351
Flunisolidum
NSC-757871
HMS2097A07
Prestwick_223
Lunis
Prestwick2_000643
Tox21_110725_1
HMS2236A06
CHEBI:5106
FLUNISOLIDE [WHO-DD]
NS00067047
Aerospan
BRD-K49577446-001-03-1
FLUNISOLIDE [MI]
(6a,11b,16a)-6-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione
Soluzione
Flunisolida
Q3746835
Pregna-1,4-diene-3,20-dione,6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-,(6a,11b,16a)-
MLS002153928
6-Fluoro-11,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione 16,17-acetonide
BPBio1_000711
Rhinalar
Syntaris Hayfever
CHEMBL1512
Nasarel
Nasalide
NCGC00179492-01
Prestwick3_000643
CS-4713

MDL Number

MFCD00133324

FAQ

What regulatory guidelines apply to (6bS,9aR,12S)-12-Fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one (CAS: 3385-03-3)?

Regulatory guidelines for (6bS,9aR,12S)-12-Fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one (CAS: 3385-03-3) include GHS classification, REACH regulations, and FDA/EPA requirements. GHS categorizes the compound based on its health and environmental hazards, while REACH regulations cover the registration, evaluation, authorization, and restriction of chemicals in the European Union. FDA and EPA have specific testing and reporting requirements for this compound, especially in pharmaceutical and biotechnological applications.

Are there alternatives to (6bS,9aR,12S)-12-Fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one (CAS: 3385-03-3) in synthesis?

In synthesis, alternatives to (6bS,9aR,12S)-12-Fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one (CAS: 3385-03-3) include structurally similar compounds such as fluoro derivatives, glycoloyl analogs, and various isomers. Common alternative reagents include fluoroacetic acid and fluoroalcohols, which can be used as precursors in synthetic pathways.

What is the market or research trend for (6bS,9aR,12S)-12-Fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one (CAS: 3385-03-3)?

The market and research trends for (6bS,9aR,12S)-12-Fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one (CAS: 3385-03-3) are centered on its use in pharmaceuticals and biotechnological applications. Recent research focuses on its potential as a precursor in drug synthesis, with ongoing studies on its efficacy and safety. Market trends show steady growth due to increasing demand in medical and research fields.

How should waste containing (6bS,9aR,12S)-12-Fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one (CAS: 3385-03-3) be handled?

Waste containing (6bS,9aR,12S)-12-Fluoro-6b-glycoloyl-5-hydroxy-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one (CAS: 3385-03-3) should be handled carefully to ensure safety and environmental protection. Waste liquid should be collected and stored in appropriate containers, labeled with the compound name and CAS number. Incineration or professional waste disposal services are recommended for this compound. Always follow local environmental regulations and guidelines for waste management.