8-{4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl}-8-azaspiro[4.5]decane-7,9-dione hydrochloride (1:1)

Basic Information

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CAS Number

33386-08-2

Molecular Formula

C21H32ClN5O2

Molecular Weight

421.97 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

201-206°C

Boiling Point

613.9°C at 760 mmHg

Density

1.24

Water Solubility

Soluble in methanol (50 mg/ml), water (partly), DMSO (100 mM).

Flash Point

9℃

SMILES

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C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4.Cl

InChI

InChI=1S/C21H31N5O2.ClH/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20;/h5,8-9H,1-4,6-7,10-17H2;1H

InChIKey

RICLFGYGYQXUFH-UHFFFAOYSA-N

LogP

2.5100000000000007

Topological Polar Surface Area

69.64000000000001 Å²

Hydrogen Bond Donor/Acceptor

0 / 7

Complexity

529

Safety Information

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GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1 Class 6.1

Toxicity

LD50 i.p. in rats: 136 mg/kg (Allen)

Synonyms & References

English

Biron
BUSPIRONE HYDROCHLORIDE [MI]
Tutran
AKOS015962019
Lucelan
1-[4-(7,9-dioxo-8-azaspiro[4.5]decan-8-yl)butyl]-4-(pyrimidin-2-yl)piperazin-1-ium chloride
Buspirone HCl pound>>MJ 9022 1 pound>> MJ-9022-1 pound>>MJ90221 pound>>MJ9022 1 pound>>MJ9022-1
Buspinol
Buspirone Hydrochloride 1.0 mg/ml in Methanol (as free base)
8-[4-[4-(2-Pyrimidinyl)-1-pipirazin yl]butyl]-8-azaspiro[4,5]decane-7,9-dione hydrochloride
Anxinil
Q-200768
33386-08-2
C21H31N5O2.HCl
Relac
APD405
1,1-Cyclopentanediacetimide, N-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, hydrochloride
SW155073-5
NCGC00260908-01
Busirone
Mabuson
8-Azaspiro[4.5]decane-7, 8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, monohydrochloride
Buspirone HCL
HY-B1115
Buspar (TN)
Hydrochloride, Buspirone
Buspirone.HCl, 1mg/ml in Methanol
BUSPIRONE HYDROCHLORIDE [JAN]
Bespar
MFCD00078569
NSC751138

MDL Number

MFCD00078569

Customs Code

2933990090

FAQ

What is 8-{4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl}-8-azaspiro[4.5]decane-7,9-dione hydrochloride (CAS: 33386-08-2)?

8-{4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl}-8-azaspiro[4.5]decane-7,9-dione hydrochloride (CAS: 33386-08-2) is a chemical compound used in pharmaceutical research. It has a complex molecular structure and is often utilized as an intermediate or precursor in the synthesis of other compounds.

What are the main uses of 8-{4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl}-8-azaspiro[4.5]decane-7,9-dione hydrochloride (CAS: 33386-08-2)?

8-{4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl}-8-azaspiro[4.5]decane-7,9-dione hydrochloride (CAS: 33386-08-2) is mainly used in pharmaceutical research for synthesizing other compounds and as a reagent in various chemical reactions.

Is 8-{4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl}-8-azaspiro[4.5]decane-7,9-dione hydrochloride (CAS: 33386-08-2) safe?

8-{4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl}-8-azaspiro[4.5]decane-7,9-dione hydrochloride (CAS: 33386-08-2) is generally safe when handled with proper precautions. It is important to follow safety guidelines, use appropriate personal protective equipment, and ensure good ventilation during handling.

How should 8-{4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl}-8-azaspiro[4.5]decane-7,9-dione hydrochloride (CAS: 33386-08-2) be stored?

8-{4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl}-8-azaspiro[4.5]decane-7,9-dione hydrochloride (CAS: 33386-08-2) should be stored in a cool, dry place away from direct sunlight. The container should be tightly sealed and kept in a well-ventilated area to prevent degradation. It should be stored at room temperature (15-25°C) and protected from high humidity and moisture.