1H-Indazol-1-amine

Basic Information

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CAS Number

33334-08-6

Molecular Formula

C7H7N3

Molecular Weight

133.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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C1=CC=C2C(=C1)C=NN2N

InChI

InChI=1S/C7H7N3/c8-10-7-4-2-1-3-6(7)5-9-10/h1-5H,8H2

InChIKey

ZWUUZXDACSQYMI-UHFFFAOYSA-N

LogP

0.7500999999999999

Topological Polar Surface Area

43.84 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

126

Synonyms & References

English

DTXSID50472031
1H-Indazol-1-amine
Indazol-1-amine
ZWUUZXDACSQYMI-UHFFFAOYSA-
MB08196
InChI=1/C7H7N3/c8-10-7-4-2-1-3-6(7)5-9-10/h1-5H,8H2
SCHEMBL18877
Indazol-1-ylamine
n-aminoindazole
MFCD09910195
AS-56979
A5948
33334-08-6
AKOS005215249
CS-0060586
N-Amino-1H-indazole
ZWUUZXDACSQYMI-UHFFFAOYSA-N
1-Amino-1H-indazole
S11721
1-aminoindazole
1‐AMINO‐1H‐INDAZOLE
indazol-1-amine
aminoindazole
azaindazole
1H-indazol-1-amine

MDL Number

MFCD09910195

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 1H-Indazol-1-amine (CAS: 33334-08-6)?

1H-Indazol-1-amine (CAS: 33334-08-6) is a crystalline solid with a molecular weight of approximately 123.17 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. The compound is reactive towards acid and base conditions. It exhibits basic properties and can form salts with acids.

How is 1H-Indazol-1-amine (CAS: 33334-08-6) typically synthesized?

1H-Indazol-1-amine is typically synthesized via two main routes: (1) from indazole through reduction methods, usually using hydrogen and a catalyst like palladium on carbon; (2) by direct amidation of indazole with an amine. The reaction yields 1H-Indazol-1-amine with good selectivity and moderate to high yield.

What industries use 1H-Indazol-1-amine (CAS: 33334-08-6)?

1H-Indazol-1-amine (CAS: 33334-08-6) finds applications in pharmaceuticals, where it can be used as a precursor in the synthesis of various bioactive compounds. It is also used in the development of organic electronic materials, particularly in semiconductors and organic light-emitting diodes (OLEDs).

What precautions should be taken when handling 1H-Indazol-1-amine (CAS: 33334-08-6)?

Handling 1H-Indazol-1-amine (CAS: 33334-08-6) requires appropriate Personal Protective Equipment (PPE) such as gloves, goggles, and a laboratory coat. It should be stored in a cool, dry environment away from heat and direct sunlight. In case of a spill, use appropriate containment and protective equipment, and consult the Safety Data Sheet (SDS) for detailed instructions on cleanup procedures.