O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate

Basic Information

View in Editor

CAS Number

333-41-5

Molecular Formula

C12H21N2O3PS

Molecular Weight

304.35 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Melting Point

>120 ºC (dec.)

Boiling Point

306 ºC

Refractive Index

nD20 1.4978-1.4981

SMILES

View in Editor

CCOP(=S)(OCC)Oc1cc(nc(n1)C(C)C)C

InChI

InChI=1S/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3

InChIKey

FHIVAFMUCKRCQO-UHFFFAOYSA-N

LogP

3.5847200000000026

Topological Polar Surface Area

53.47 Å²

Hydrogen Bond Donor/Acceptor

0 / 5

Complexity

307

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

H410

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 3 Class 3

Sensitiveness

对光敏感

Toxicity

LD50 in male, female rats (mg/kg): 250, 285 orally (Gaines)

Synonyms & References

English

Diazinon
Dimpylate
Basudin
Diazitol
o,o-diethyl o-2-isopropyl-4-methyl-6-pyrimidyl thiophosphate
o,o-diethyl o-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl) phosophorothioate
Diazinon solution
Diazinon granule
AG-500
Anti
Antlak
Dazzel
Diazinon AG500
Diazinon100µg
Dicid
dyzol
Exodin
G 301
O,O-diethyl O-[6-methyl-2-(1-methylethyl)-4-pyrimidinyl] phosphorothioate
O,O-diethyl O-[6-methyl-2-(propan-2-yl)pyrimidin-4-yl] phosphorothioate
O,O-diethyl O-2-isopropyl-6-methylpyrimidin-4-yl phosphorothioate
pt265
O,O-Diethyl O-2-isopropyl-4-methyl-6-pyrimidyl thiophosphate
O,O-Diethyl O-(6-methyl-2-(1-methylethyl)-4-pyrimidinyl) phosophorothioate

MDL Number

MFCD00036204

FAQ

What is O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate (CAS: 333-41-5)?

O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate (CAS: 333-41-5) is an organophosphate compound with the chemical formula C9H17N2O3PS. It features a thiophosphate group linked to a pyrimidine ring substituted with isopropyl and methyl groups. This compound is known for its pesticidal properties and is commonly used as an insecticide due to its ability to disrupt neuromuscular function in pests. Its structure makes it a valuable intermediate in organic synthesis and research.

What are the main uses of O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate (CAS: 333-41-5)?

O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate (CAS: 333-41-5) is primarily used as a pesticide, specifically targeting insects. It is also employed in agricultural chemicals for crop protection. In research, it serves as a key compound for studying organophosphate mechanisms and developing new insecticidal agents. Additionally, it acts as an intermediate in the synthesis of pharmaceuticals and other organic compounds, contributing to drug discovery and chemical innovation.

Is O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate (CAS: 333-41-5) safe?

Safety of O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate (CAS: 333-41-5) depends on proper handling. It is toxic to humans and animals, particularly via inhalation or skin contact, and may cause irritation or more severe health effects. Safety standards require protective measures like gloves, goggles, and ventilation. It is classified as a hazardous substance under OSHA and EPA guidelines, so adherence to safety protocols and regulatory compliance is essential when working with this compound.

How should O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate (CAS: 333-41-5) be stored?

O,O-Diethyl O-(2-isopropyl-6-methyl-4-pyrimidinyl) phosphorothioate (CAS: 333-41-5) should be stored in a cool, dry, and dark place, ideally at 2-8°C. Keep it in a sealed container to prevent moisture exposure and maintain stability. Avoid contact with incompatible materials and ensure storage in a well-ventilated area. Proper labeling and secure storage are critical to prevent accidental spills or contamination, preserving its efficacy and safety.