6-Chloro-2-pyridinecarbonitrile

Basic Information

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CAS Number

33252-29-8

Molecular Formula

C6H3ClN2

Molecular Weight

17.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

85-89 °C

Boiling Point

245.3 °C at 760 mmHg

Density

1.33

Flash Point

102.1℃

Refractive Index

1.565

SMILES

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C1=CC(=NC(=C1)Cl)C#N

InChI

InChI=1S/C6H3ClN2/c7-6-3-1-2-5(4-8)9-6/h1-3H

InChIKey

PGZHSVWXFKKCNR-UHFFFAOYSA-N

LogP

0.16199999999999998

Topological Polar Surface Area

35.0 Å²

Hydrogen Bond Donor/Acceptor

3 / 1

Complexity

137

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

UNII-ZS4YVY14OF
SCHEMBL938230
EN300-73839
2-CHLOROPYRIDINE-6-CARBONITRILE
AM62387
J-019113
6-Chloro-pyridine-2-carbonitrile
BCP21812
2-cyano-6-chloropyridine
2-Pyridinecarbonitrile, 6-chloro-
2-Chloro-6-cyanopyridine
FT-0648086
6-Chloro-2-pyridinecarbonitrile
A5934
AKOS002663150
NS00029448
Z1162911438
DTXSID40186897
Pyridine, 2-carbonitrile-6-chloro-
SY012070
6-Chloropicolinonitrile
EINECS 251-429-7
AC-9488
6-Chloro-2-pyridinecarbonitrile #
AB05877
6-Chloro-2-cyanopyridine
6-Chloropyridine-2-carbonitrile
33252-29-8
J-518650
6-Chloropyridine-2-carbonitrile, 96%
MFCD00274527

MDL Number

MFCD00274527

Customs Code

2933399090

FAQ

What regulatory guidelines apply to 6-Chloro-2-pyridinecarbonitrile (CAS: 33252-29-8)?

6-Chloro-2-pyridinecarbonitrile (CAS: 33252-29-8) is regulated under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), which includes health and environmental hazard classifications. It falls under REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) in the European Union, requiring substance registration and safety data sheets (SDS). Additionally, it must comply with FDA (Food and Drug Administration) and EPA (Environmental Protection Agency) regulations in the United States, particularly concerning its handling and disposal.

Are there alternatives to 6-Chloro-2-pyridinecarbonitrile (CAS: 33252-29-8) in synthesis?

Synthesizing 6-Chloro-2-pyridinecarbonitrile (CAS: 33252-29-8) can be achieved using alternative reagents and methods. For instance, analogous compounds like 6-bromo-2-pyridinecarbonitrile or 2-pyridinecarbonitrile can be used as alternatives. Different synthetic routes, such as nucleophilic substitutions or cyanation reactions with different electrophiles, can also provide alternatives depending on the desired properties of the final product.

What is the market or research trend for 6-Chloro-2-pyridinecarbonitrile (CAS: 33252-29-8)?

The market for 6-Chloro-2-pyridinecarbonitrile (CAS: 33252-29-8) is driven by its use in pharmaceuticals and agrochemicals due to its stabilizing and functionalizing properties. Research trends focus on its application in developing new drug delivery systems and improving crop protection. Market demand is also influenced by increasing agricultural needs and pharmaceutical innovations, with ongoing research exploring its potential in these fields.

How should waste containing 6-Chloro-2-pyridinecarbonitrile (CAS: 33252-29-8) be handled?

Waste containing 6-Chloro-2-pyridinecarbonitrile (CAS: 33252-29-8) should be collected in appropriate containers and stored under controlled conditions to prevent environmental contamination. Professional waste disposal services should be utilized for safe incineration or other disposal methods. Proper environmental protection measures should be taken to handle and transport the waste, ensuring compliance with local and international regulations to minimize ecological impact.