(2R)-2-{[(tert-butoxy)carbonyl]amino}-2-phenylacetic acid

Basic Information

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CAS Number

33125-05-2

Molecular Formula

C13H17NO4

Molecular Weight

251.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

89.0 to 93.0 deg-C

Boiling Point

407.2°C at 760 mmHg

Density

1.1820

Water Solubility

Insoluble in water. Slightly soluble in DMSO and methanol.

Flash Point

200.1°C

Refractive Index

-140 ° (C=1, EtOH)

Specific Rotation

-142 º (c=1% in ethanol)

SMILES

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CC(C)(C)OC(=O)NC(C1=CC=CC=C1)C(=O)O

InChI

InChI=1S/C13H17NO4/c1-13(2,3)18-12(17)14-10(11(15)16)9-7-5-4-6-8-9/h4-8,10H,1-3H3,(H,14,17)(H,15,16)/t10-/m1/s1

InChIKey

HOBFSNNENNQQIU-SNVBAGLBSA-N

LogP

2.3370000000000006

Topological Polar Surface Area

75.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

303

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

UNII-4PFG3246TW
Boc-L-
Z756462186
(R)-[(tert-butoxycarbonyl)amino](phenyl)acetic acid
M03222
(R)-2-(Boc-amino)-2-phenylacetic Acid
B3230
tert-Butyloxycarbonyl D-alpha-phenylglycine
(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-2-phenylacetic acid
Benzeneacetic acid, alpha-[[(1,1-dimethylethoxy)carbonyl]amino]-, (R)-
(R)-tert-butoxycarbonylamino-phenylacetic acid
AKOS015922795
(alphaR)-alpha-[[(1,1-Dimethylethoxy)carbonyl]amino]-benzeneacetic Acid
Benzeneacetic acid, alpha-(((1,1-dimethylethoxy)carbonyl)amino)-, (R)-
AC-24141
A-[[(1,1-Dimethylethoxy)carbonyl]amino]benzeneacetic acid
(alphaR)-alpha-[[(1,1-Dimethylethoxy)carbonyl]amino]benzeneacetic acid
N-Boc-L-phenylglycine
N-(tert-Butoxycarbonyl)-2-phenylglycine
'(R)-tert-Butoxycarbonylamino-phenyl
J-019033
EN300-52858
4PFG3246TW
(2R)-2-{[(tert-butoxy)carbonyl]amino}-2-phenylacetic acid
Benzeneacetic acid, alpha-(((1,1-dimethylethoxy)carbonyl)amino)-, (alphaR)-
(R)-2-((tert-Butoxycarbonyl)amino)-2-phenylacetic acid
(R)-TERT-BUTOXYCARBONYLAMINO-PHENYL-ACETIC ACID
HOBFSNNENNQQIU-SNVBAGLBSA-N
n-boc l-phenylglycine
HY-34663
(

MDL Number

MFCD00062043

Customs Code

2924299090

FAQ

What regulatory guidelines apply to (2R)-2-{[(tert-butoxy)carbonyl]amino}-2-phenylacetic acid (CAS: 33125-05-2)?

Regulatory guidelines for (2R)-2-{[(tert-butoxy)carbonyl]amino}-2-phenylacetic acid (CAS: 33125-05-2) include GHS classification, which categorizes it as a substance of low concern. For EU manufacturers and importers, it must comply with REACH regulations. FDA and EPA may have specific requirements regarding its use in pharmaceuticals and environmental handling respectively. Detailed documentation on safety data sheets and product labels is essential for compliance.

Are there alternatives to (2R)-2-{[(tert-butoxy)carbonyl]amino}-2-phenylacetic acid (CAS: 33125-05-2) in synthesis?

Yes, several alternatives can be used in the synthesis of (2R)-2-{[(tert-butoxy)carbonyl]amino}-2-phenylacetic acid (CAS: 33125-05-2). Common alternatives include (2S)-2-{[(tert-butoxy)carbonyl]amino}-2-phenylacetic acid and related carboxylic acids. Researchers often explore these due to their structural similarities and potential for easier synthesis. Synthesis might also involve the use of different protecting groups or additional functional groups to simplify the process.

What is the market or research trend for (2R)-2-{[(tert-butoxy)carbonyl]amino}-2-phenylacetic acid (CAS: 33125-05-2)?

The market and research trends for (2R)-2-{[(tert-butoxy)carbonyl]amino}-2-phenylacetic acid (CAS: 33125-05-2) are focused on its application in pharmaceuticals and as an intermediate in synthetic pathways. Recent research trends include its use in drug development and biotechnology applications. Market demand is expected to grow due to increasing interest in personalized medicine and the need for novel therapeutic agents.

How should waste containing (2R)-2-{[(tert-butoxy)carbonyl]amino}-2-phenylacetic acid (CAS: 33125-05-2) be handled?

Waste containing (2R)-2-{[(tert-butoxy)carbonyl]amino}-2-phenylacetic acid (CAS: 33125-05-2) should be managed through proper waste liquid collection and subsequent incineration or professional waste disposal services. Environmental protection precautions include ensuring the waste is neutralized and treated to minimize environmental impact. It is crucial to follow local regulations and guidelines for hazardous waste disposal to ensure safety and compliance.