Avanafil Impurity 15

Basic Information

View in Editor

CAS Number

330784-47-9

Molecular Formula

C23H26ClN7O3

Molecular Weight

483.96 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

Powder

Melting Point

150-152°C

SMILES

View in Editor

COC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCCC4CO)Cl

InChI

InChI=1S/C23H26ClN7O3/c1-34-19-6-5-15(10-18(19)24)11-27-21-17(22(33)28-13-20-25-7-3-8-26-20)12-29-23(30-21)31-9-2-4-16(31)14-32/h3,5-8,10,12,16,32H,2,4,9,11,13-14H2,1H3,(H,28,33)(H,27,29,30)/t16-/m0/s1

InChIKey

WEAJZXNPAWBCOA-INIZCTEOSA-N

LogP

2.4318

Topological Polar Surface Area

125.39000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 10

Complexity

642

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

TA-1790
4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
SW219217-1
AVANAFIL [VANDF]
4-{[(3-chloro-4-methoxyphenyl)methyl]amino}-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-[(pyrimidin-2-yl)methyl]pyrimidine-5-carboxamide
Avanafil (USAN/INN)
s4019
J-019006
(S)-4-[(3-Chlor-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1- pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamid
GTPL7448
CCG-229896
DR5S136IVO
DB06237
NS00014947
AVANAFIL [MI]
BDBM50036629
AMY1794
Avanafil 100 microg/mL in Acetonitrile:Dimethylsulfoxide
Z2235802070
G04BE10
STENDRA
(S)-2-(2-hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[N-(2-pyrimidylmethyl)carbamoyl]-pyrimidine
D03217
DTXCID90109218
NCGC00386241-01
HY-18252
Stendra (TN)
CHEBI:66876
C23H26ClN7O3
Q2873270
AVANAFIL [USAN]

MDL Number

MFCD11977961

Customs Code

2933990090

FAQ

What is Avanafil Impurity 15 (CAS: 330784-47-9)?

Avanafil Impurity 15 (CAS: 330784-47-9) is a chemical compound identified as a byproduct during the synthesis of Avanafil, a PDE5 inhibitor used in pharmaceuticals. It is typically characterized by its structural similarity to Avanafil and is used in quality control and research to ensure drug purity. Its exact chemical formula and molecular structure may vary depending on the synthesis pathway.

What are the main uses of Avanafil Impurity 15 (CAS: 330784-47-9)?

Avanafil Impurity 15 (CAS: 330784-47-9) is primarily used in pharmaceutical research for analytical testing, drug impurity profiling, and regulatory compliance. It may also serve as a reference standard in quality control processes to identify and quantify trace impurities in Avanafil preparations, ensuring safety and efficacy in drug development.

Is Avanafil Impurity 15 (CAS: 330784-47-9) safe?

Avanafil Impurity 15 (CAS: 330784-47-9) is not intended for human or veterinary use and should be handled with appropriate safety measures. While specific toxicity data may not be widely available, it is generally considered low risk when used in controlled laboratory settings. Always follow standard chemical safety protocols, including personal protective equipment (PPE) and proper disposal methods.

How should Avanafil Impurity 15 (CAS: 330784-47-9) be stored?

Avanafil Impurity 15 (CAS: 330784-47-9) should be stored in a cool, dry place, away from light and moisture. Keep it in a tightly sealed container to prevent contamination and degradation. Maintain storage conditions between 15-25°C (59-77°F) and avoid exposure to air or heat to ensure stability and prolong shelf life.