(3R,4R)-Tert-butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate | CAS No. 330681-18-0

(3R,4R)-Tert-butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate

Basic Information

CAS Number

330681-18-0

Molecular Formula

C9H18N2O3

Molecular Weight

202.25 g/mol

AD

Basic Physical Properties

CC(C)(C)OC(=O)N1CC(C(C1)O)N

InChI

InChI=1S/C9H18N2O3/c1-9(2,3)14-8(13)11-4-6(10)7(12)5-11/h6-7,12H,4-5,10H2,1-3H3/t6-,7-/m1/s1

InChIKey

MOZOQDNRVPHFOO-RNFRBKRXSA-N

LogP

-0.07470000000000021

Topological Polar Surface Area

75.78999999999999 Ų

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

225

Safety Information

View Safety Information

Hazard Class

Class 8 Class 8

Synonyms & References

English

  • (3R,4R)-tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate
  • 1-Pyrrolidinecarboxylicacid,3-amino-4-hydroxy-,1,1-dimethylethylester,(3R,4R)-(9CI)
  • (3R,4R)-(-)-1-Benzyl-3,4-pyrrolidinedi
  • (3R,4R)-1-benzyl-3,4-diaminopyrrolidine
  • (3R,4R)-3,4-diamino-1-benzylpyrrolidine
  • (3R,4R)-3-amino-1-hydroxy-4-methyl-pyrrolidin-2-one*acetic acid
  • (3R,4R)-3-amino-4-hydroxy-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester
  • (3R,4R)-4-amino-3-hydroxy-1-pyrrolidinecarboxylate
  • 1,1-dimethylethyl ester
  • ANW-20549
  • D4035
  • N-benzyl 3R,4R-diaminopyrrolidine
  • SureCN5836807
  • tert-butyl (3R,4R)-3-amino-4-hydroxypyrrolidine-1-carboxylate
  • DS-8649
  • AKOS015854201
  • 1-Boc-(3R,4R)-3-amino-4-hydroxypyrrolidine
  • (3R,4R)-3-Amino-4-hydroxy-1-pyrrolidinecarboxylic acid, 1,1-dimethylethyl ester
  • tert-Butyl (3R,4R)-3-amino-4-hydroxy-pyrrolidine-1-carboxylate
  • A3246
  • EN300-248829
  • AMY6784
  • (3R,4R)-3-amino-4-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester
  • (3R,4R)-TERT-BUTYL 3-AMINO-4-HYDROXYPYRROLIDINE-1-CARBOXYLATE
  • trans-1-Boc-3-aminopyrrolidin-4-ol
  • (3R,4R)-rel-tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate
  • (3R,4R)- 3-Amino-4-hydroxy-1-pyrrolidinecarboxylic acid, 1,1-dimethylethyl ester
  • 330681-18-0
  • MOZOQDNRVPHFOO-RNFRBKRXSA-N
  • rac-tert-butyl (3R,4R)-3-amino-4-hydroxypyrrolidine-1-carboxylate
  • 148214-90-8

MDL Number

MFCD11111251

FAQ

What is (3R,4R)-Tert-butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate (CAS: 330681-18-0)?

(3R,4R)-Tert-butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate (CAS: 330681-18-0) is a chiral organic compound with a tertiary butyl group attached to the pyrrolidine ring. It is commonly used as an intermediate in the synthesis of pharmaceuticals and other chemicals.

What are the main uses of (3R,4R)-Tert-butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate (CAS: 330681-18-0)?

(3R,4R)-Tert-butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate (CAS: 330681-18-0) is primarily used as a chiral auxiliary in the synthesis of enantiomerically pure compounds, particularly in pharmaceuticals and agrochemicals. It is also utilized in the development of new drug candidates and as a building block in organic synthesis.

Is (3R,4R)-Tert-butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate (CAS: 330681-18-0) safe?

(3R,4R)-Tert-butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate (CAS: 330681-18-0) is generally considered safe when handled properly. However, it is important to follow safety guidelines, such as wearing protective gloves and goggles, and ensuring good ventilation. Exposure to the compound should be minimized to avoid skin contact and inhalation.

How should (3R,4R)-Tert-butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate (CAS: 330681-18-0) be stored?

(3R,4R)-Tert-butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate (CAS: 330681-18-0) should be stored in a tightly sealed container in a cool, dry place away from direct sunlight and heat sources. The storage temperature should be maintained between 15°C and 25°C to prevent degradation. Ensure the storage area has good ventilation to avoid the accumulation of flammable vapors.

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