2,5-Bis(trifluoromethyl)aniline

Basic Information

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CAS Number

328-93-8

Molecular Formula

C8H5F6N

Molecular Weight

229.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

177°C

Refractive Index

n20/D 1.432(lit.)

SMILES

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C1=CC(=C(C=C1C(F)(F)F)N)C(F)(F)F

InChI

InChI=1S/C8H5F6N/c9-7(10,11)4-1-2-5(6(15)3-4)8(12,13)14/h1-3H,15H2

InChIKey

XWMVIJUAZAEWIE-UHFFFAOYSA-N

LogP

3.3064

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

220

Safety Information

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GHS Hazard Pictograms

H302

H312

H315

H319

H332

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

EN300-02439
NS00126766
FT-0610260
2,5-Bis(trifluoromethyl)-aniline
Z56896763
2,5-bis-trifluoromethyl-aniline
Benzenamine, 2,5-bis(trifluoromethyl)-
2,5-di(trifluoromethyl)aniline
2,5-BIS(TRIFLUOROMETHYL)BENZENAMINE
2,5-bis-trifluoromethylanilin
alpha,alpha,alpha,alphaatrade mark,alphaatrade mark,alphaatrade mark-hexafluoro-2,5-Xylidine; 2,5-Bis(trifluoromethyl)aniline; 2,5-Bis(trifluoromethyl)benzenamine; 2,5-Di(trifluoromethyl)aniline; alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro-2,5-Xylidine
DTXSID00352132
BCP08855
Enamine_005232
328-93-8
AC-3652
J-507275
2,5-Bis(trifluoromethyl)aniline
HMS1408N18
AM20060382
CS-W007922
2,5-Bis (trifluoro methyl) aniline
AKOS000115443
MFCD00074940
2,5-bis-trifluoromethylaniline
SCHEMBL330502
alpha,alpha,alpha,alpha',alpha',alpha'-Hexafluoro-2,5-xylidine
2,5-ditrifluoromethylaniline
2,5-bis-(Trifluoromethyl)aniline
IDI1_007819
2,5-Bis(trifluoromethyl)aniline, 99%

MDL Number

MFCD00074940

Customs Code

2921420090

FAQ

What is 2,5-Bis(trifluoromethyl)aniline (CAS: 328-93-8)?

2,5-Bis(trifluoromethyl)aniline is a colorless crystalline compound with the CAS number 328-93-8. It has a molecular formula of C7H3F3N and is commonly used in the synthesis of pharmaceuticals and dyes. It is known for its high boiling point and low solubility in water.

What are the main uses of 2,5-Bis(trifluoromethyl)aniline (CAS: 328-93-8)?

2,5-Bis(trifluoromethyl)aniline is primarily used in the pharmaceutical industry for the preparation of drugs, such as antitumor agents. It is also utilized in the dye industry for the production of certain types of pigments. Additionally, it serves as a key intermediate in the synthesis of various organic compounds.

Is 2,5-Bis(trifluoromethyl)aniline (CAS: 328-93-8) safe?

2,5-Bis(trifluoromethyl)aniline is considered to have moderate toxicity. It is important to handle it with appropriate protective equipment, such as gloves and a respirator, due to its potential respiratory and skin irritation. It is crucial to follow safety standards and guidelines provided by OSHA and other regulatory bodies.

How should 2,5-Bis(trifluoromethyl)aniline (CAS: 328-93-8) be stored?

2,5-Bis(trifluoromethyl)aniline should be stored in a cool, dry place, away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent exposure to air and moisture. The storage temperature should be maintained between 15-25°C (59-77°F), and the relative humidity should be below 60%. Proper ventilation is essential to minimize the risk of inhalation exposure.