1-Bromo-3,5-bis(trifluoromethyl)benzene

Basic Information

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CAS Number

328-70-1

Molecular Formula

C8H3BrF6

Molecular Weight

293 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

−16 °C

Boiling Point

151°C

Water Solubility

Immiscible with water.

Refractive Index

n20/D 1.427(lit.)

SMILES

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C1=C(C=C(C=C1C(F)(F)F)Br)C(F)(F)F

InChI

InChI=1S/C8H3BrF6/c9-6-2-4(7(10,11)12)1-5(3-6)8(13,14)15/h1-3H

InChIKey

CSVCVIHEBDJTCJ-UHFFFAOYSA-N

LogP

4.486700000000001

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

198

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

HY-75088
MFCD00000381
AC-9664
3,5-bis-(trifluoromethyl)-bromobenzene
3,5-bistrifluoromethylbromobenzene
3,5-di(Trifluoromethyl)bromobenzene
NSC 88284
Benzene, 1-bromo-3,5-bis(trifluoromethyl)-
328-70-1
3,5-Ditrifluoromethylbromobenzene
1,3-Bis(trifluoromethyl)-5-bromobenzene
1-Bromo-3,5-bis(trifluoromethyl)benzene #
1,3-Bis(trifluoromethyl)-5-bromobenzene, 99%
3,5-bis(trifluoromethyl)bromo benzene
3,5-B is(trifluoromethyl)bromobenzene
B1753
3,5-bis-trifluoromethyl-bromobenzene
NS00041864
NSC88284
A5873
Q-200347
3,5-Bis(trifluoromethyl)bromobenzene
m-Xylene, 5-bromo-alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro-
3.5-Bis(Trifluoromethyl)Bromobenzene
1-BOC-2-[(4-BROMO-PHENYLAMINO)-METHYL]-PIPERIDINE
3,5-di(trifluoromethyl)phenyl bromide
3,5bis(trifluoromethyl)bromobenzene
AM61477
1-bromo-3,5-bis(trifluoromethyl)-benzene
3,5-bis-trifluoromethylbromobenzene
EINECS 206-334-5

MDL Number

MFCD00000381

Customs Code

29036990

FAQ

What is 1-Bromo-3,5-bis(trifluoromethyl)benzene (CAS: 328-70-1)?

1-Bromo-3,5-bis(trifluoromethyl)benzene (CAS: 328-70-1) is an aromatic brominated compound with the chemical formula C8H6BrF6. It features a benzene ring substituted with a bromo group at position 1 and trifluoromethyl groups at positions 3 and 5. This compound is a colorless liquid with low solubility in water but higher solubility in organic solvents. Its high fluorine content contributes to chemical stability and unique reactivity patterns, making it significant in organic synthesis and industrial applications.

What are the main uses of 1-Bromo-3,5-bis(trifluoromethyl)benzene (CAS: 328-70-1)?

1-Bromo-3,5-bis(trifluoromethyl)benzene (CAS: 328-70-1) is primarily used as a key intermediate in pharmaceutical and agrochemical industries. It serves as a building block for synthesizing fluorinated drugs and pesticides, leveraging its bromo and trifluoromethyl functional groups. Additionally, it finds applications in materials science for producing fluorinated polymers and specialty chemicals. Its unique structure also supports research in organic chemistry and chemical modification processes.

Is 1-Bromo-3,5-bis(trifluoromethyl)benzene (CAS: 328-70-1) safe?

1-Bromo-3,5-bis(trifluoromethyl)benzene (CAS: 328-70-1) is considered hazardous and requires careful handling. It may cause skin and eye irritation, and prolonged exposure can lead to respiratory issues. Safety standards advise using appropriate protective equipment, such as gloves and goggles, and working in well-ventilated areas. Proper storage and adherence to OSHA guidelines are essential to minimize risks associated with its chemical properties.

How should 1-Bromo-3,5-bis(trifluoromethyl)benzene (CAS: 328-70-1) be stored?

1-Bromo-3,5-bis(trifluoromethyl)benzene (CAS: 328-70-1) should be stored in a cool, dry, and dark place to maintain stability. Keep it in a sealed, airtight container made of inert material to prevent moisture and air exposure. Avoid high temperatures and humidity, as these may affect its chemical integrity. Storage conditions must comply with safety regulations to ensure long-term preservation and prevent hazardous reactions.