3-(1-methylpyrrolidin-2-yl)pyridin-2-amine | CAS No. 32726-84-4
3-(1-methylpyrrolidin-2-yl)pyridin-2-amine
Basic Information
CAS Number
32726-84-4
Molecular Formula
C10H15N3
Molecular Weight
177.25 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- 3-(1-methylpyrrolidin-2-yl)pyridin-2-amine
- IDI1_009268
- J-018860
- 32726-84-4
- AKOS016344452
- 3-(1-Methyl-2-pyrrolidinyl)-2-pyridinylamine #
- Oprea1_035600
- Cambridge id 5103926
- IFQQQYVVFJFUMU-UHFFFAOYSA-N
- 6969-91-1
- AKOS000365961
- HMS1415P15
- 3-(1-Methyl-pyrrolidin-2-yl)-pyridin-2-ylamine
- BB 0261570
- CBDivE_000365
- SR-01000406230
- 3-(1-Methyl-2-pyrrolidinyl-2-pyridinamine
- NCIOpen2_000445
- SCHEMBL7696569
- Nicotine, 2-amino-, (+-)-
- SR-01000406230-1
- rac-2-Amino Nicotine
- MFCD00540700
- NSC68655
- Pyridine, 2-amino-3-(1-methylpyrrolidin-2-yl)-
- (+-)-2-Aminonicotine
- SB36616
- IFLab1_001401
- DTXSID40954391
- NSC-68655
- EU-0068828
MDL Number
MFCD00540700
Customs Code
2933990090
FAQ
What are the physical and chemical properties of 3-(1-methylpyrrolidin-2-yl)pyridin-2-amine (CAS: 32726-84-4)?
3-(1-methylpyrrolidin-2-yl)pyridin-2-amine is a crystalline solid with a molecular weight of approximately 228.33 g/mol. It has a low solubility in water (0.1 g/100 mL at 25°C) and good solubility in organic solvents like dichloromethane and ethanol. The compound is moderately reactive, showing basic properties due to the amine group. It is stable under normal conditions but should be stored in a cool, dry place away from strong acids and oxidizers.
How is 3-(1-methylpyrrolidin-2-yl)pyridin-2-amine (CAS: 32726-84-4) typically synthesized?
3-(1-methylpyrrolidin-2-yl)pyridin-2-amine is typically synthesized via a multi-step process involving the reaction of 2-chloropyridine with 1-methylpyrrolidine. The reaction is catalyzed by a base such as potassium carbonate, and the product is isolated by recrystallization. The yield is usually around 70-80%, and the method is known for its good selectivity and moderate reaction time.
What industries use 3-(1-methylpyrrolidin-2-yl)pyridin-2-amine (CAS: 32726-84-4)?
3-(1-methylpyrrolidin-2-yl)pyridin-2-amine is primarily used in the pharmaceutical industry due to its potential as a therapeutic agent. It is also explored for use in sensor technology and as a precursor in the synthesis of other compounds. Its chemical properties make it suitable for applications requiring basic functionalities and specific structural characteristics.
What precautions should be taken when handling 3-(1-methylpyrrolidin-2-yl)pyridin-2-amine (CAS: 32726-84-4)?
When handling 3-(1-methylpyrrolidin-2-yl)pyridin-2-amine, it is important to use personal protective equipment (PPE) such as gloves and safety goggles. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up carefully, and the area should be flushed with water. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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