1,2,4,5-Tetrafluorobenzene

Basic Information

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CAS Number

327-54-8

Molecular Formula

C6H2F4

Molecular Weight

150.07 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

4 °C

Boiling Point

90°C

Water Solubility

Not miscible or difficult to mix in water.

Refractive Index

n20/D 1.407(lit.)

SMILES

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C1=C(C(=CC(=C1F)F)F)F

InChI

InChI=1S/C6H2F4/c7-3-1-4(8)6(10)2-5(3)9/h1-2H

InChIKey

SDXUIOOHCIQXRP-UHFFFAOYSA-N

LogP

2.2430000000000003

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

90.3

Safety Information

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Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 3 Class 3

Synonyms & References

English

FT-0631958
A821398
1,2,4,5-tetrafluoro-benzene
NS00041536
1,2,4,5-tetrakis(fluoranyl)benzene
GS-3490
Benzene, 1,2,4,5-tetrafluoro-
s10424
W-106824
1,2,4,5-Tetrafluorobenzene, >=99%
327-54-8
AM20040175
2,3,5,6-Tetrafluorobenzene;p-Tetrafluorobenzene
EN300-97145
DTXSID90186367
1,4,5-Tetrafluorobenzene
1, 2, 4, 5-tetrafluorobenzene
CS-0020157
EINECS 206-319-3
2,3,5,6-Tetrafluorobenzene
2,5,6-Tetrafluorobenzene
1,2,4,5-TETRAFLUOROBENZENE
NSC-10249
AB3CL8US2H
NSC10249
SCHEMBL530766
2,3,5,6-tetrafluoro benzene
Z1203162141
AKOS006223912
AC-10613
T1029

MDL Number

MFCD00000307

Customs Code

2903999090

FAQ

What are the physical and chemical properties of 1,2,4,5-Tetrafluorobenzene (CAS: 327-54-8)?

1,2,4,5-Tetrafluorobenzene (CAS: 327-54-8) is a colorless, crystalline solid with a high melting point of 129-130°C. Its molecular weight is approximately 188.08 g/mol. It is slightly soluble in water but soluble in organic solvents like benzene and chloroform. Chemically, it is relatively inert but can undergo electrophilic substitution reactions under certain conditions.

How is 1,2,4,5-Tetrafluorobenzene (CAS: 327-54-8) typically synthesized?

1,2,4,5-Tetrafluorobenzene (CAS: 327-54-8) is typically synthesized through the fluorination of benzene using fluorine gas. This process requires careful control of temperature and pressure to achieve the desired selectivity and yield. The reaction often uses a catalyst like ferric fluoride to enhance the reaction rate and control the fluorination process.

What industries use 1,2,4,5-Tetrafluorobenzene (CAS: 327-54-8)?

1,2,4,5-Tetrafluorobenzene (CAS: 327-54-8) is used in various industries, including pharmaceuticals, where it serves as a precursor for fluorinated drugs; polymers, where it can be incorporated into the polymer structure for specific properties; and electronics, particularly in sensors and semiconductor devices due to its unique electronic properties.

What precautions should be taken when handling 1,2,4,5-Tetrafluorobenzene (CAS: 327-54-8)?

When handling 1,2,4,5-Tetrafluorobenzene (CAS: 327-54-8), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood to avoid inhalation. In case of a spill, it should be cleaned up carefully following proper laboratory safety protocols. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and emergency procedures.