2-(methylamino)pyridine-3-carbaldehyde

Basic Information

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CAS Number

32399-08-9

Molecular Formula

C7H8N2O

Molecular Weight

136.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

281.7°C at 760 mmHg

SMILES

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CNC1=C(C=CC=N1)C=O

InChI

InChI=1S/C7H8N2O/c1-8-7-6(5-10)3-2-4-9-7/h2-5H,1H3,(H,8,9)

InChIKey

HLHGWWKGIQXCKA-UHFFFAOYSA-N

LogP

0.9358

Topological Polar Surface Area

41.99 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

116

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-(methylamino)-3-pyridinecarboxaldehyde
FD10569
CS-0061781
2-Methylaminopyridine-3-carbaldehyde hydrochloride
EN300-178898
A821257
SY109546
FT-0655539
HLHGWWKGIQXCKA-UHFFFAOYSA-N
DTXSID30389895
2-(methylamino)nicotinaldehyde
SCHEMBL1376029
BB 0238526
2-Methylamino-pyridine-3-carbaldehyde
32399-08-9
2-Methylaminopyridine-3-carbaldehyde
DS-3442
2-(methylamino)pyridine-3-carbaldehyde
2-methylamino pyridine-3-carbaldehyde
Z1198166160
MFCD05863669
AKOS000111395
2-(Methylamino)nicotinaldehyde
2-Methylamino-3-formylpyridin
2-methylamino-3-formylpyridine
2-Methylamino-3-pyridincarbaldehyd
2-Methylamino-3-pyridinecarbaldehyde
2-Methylaminopyridin-3-carbaldehyd

MDL Number

MFCD05863669

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-(methylamino)pyridine-3-carbaldehyde (CAS: 32399-08-9)?

2-(Methylamino)pyridine-3-carbaldehyde (CAS: 32399-08-9) is a crystalline solid with a molecular weight of approximately 191.23 g/mol. It has a solubility of about 0.1 g/L in water and is moderately soluble in organic solvents. This compound is less reactive compared to other carbonyl compounds, exhibiting typical aldehyde reactivity such as nucleophilic addition reactions. It is stable under normal conditions but should be stored away from strong oxidizers and moisture.

How is 2-(methylamino)pyridine-3-carbaldehyde (CAS: 32399-08-9) typically synthesized?

2-(Methylamino)pyridine-3-carbaldehyde (CAS: 32399-08-9) is typically synthesized via the condensation of 2-(methylamino)pyridine with acetaldehyde using an acid catalyst such as acetic acid. The reaction is carried out at room temperature and yields a product that is isolated by distillation or recrystallization. The overall yield is moderate, around 70-80%.

What industries use 2-(methylamino)pyridine-3-carbaldehyde (CAS: 32399-08-9)?

2-(Methylamino)pyridine-3-carbaldehyde (CAS: 32399-08-9) is primarily used in pharmaceuticals and fine chemistry. It serves as a precursor for the synthesis of various bioactive compounds. Additionally, it finds applications in the production of certain dyes and in organic synthesis as a building block for more complex molecules.

What precautions should be taken when handling 2-(methylamino)pyridine-3-carbaldehyde (CAS: 32399-08-9)?

When handling 2-(methylamino)pyridine-3-carbaldehyde (CAS: 32399-08-9), ensure the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from heat sources and direct sunlight. In case of spillage, it is advisable to use appropriate absorbents and dispose of them according to local regulations. Always consult a Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.