6-(Benzyloxy)-3,4-dihydro-1(2H)-naphthalenone

Basic Information

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CAS Number

32263-70-0

Molecular Formula

C17H16O2

Molecular Weight

252.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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C1CC2=C(C=CC(=C2)OCC3=CC=CC=C3)C(=O)C1

InChI

InChI=1S/C17H16O2/c18-17-8-4-7-14-11-15(9-10-16(14)17)19-12-13-5-2-1-3-6-13/h1-3,5-6,9-11H,4,7-8,12H2

InChIKey

SAYPPJQQGVXKAP-UHFFFAOYSA-N

LogP

3.784600000000003

Topological Polar Surface Area

26.3 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

306

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

6-phenylmethoxy-3,4-dihydro-2H-naphthalen-1-one
CX1256
AKOS011105275
CHEMBL3288291
A918174
3,4-dihydro-6-(phenylmethoxy)-1(2H)-naphthalenone
SCHEMBL226640
6-(benzyloxy)-3,4-dihydronaphthalen-1(2H)-one
1(2H)-Naphthalenone, 3,4-dihydro-6-(phenylmethoxy)-
32263-70-0
ZB1840
J-518042
SAYPPJQQGVXKAP-UHFFFAOYSA-N
6-benzyloxy-3,4-dihydronaphthalen-1(2H)-one
6-(benzyloxy)-1,2,3,4-tetrahydronaphthalen-1-one
6-(benzyloxy)-3,4-dihydronaphthalene-1(2H)-one
CS-B1524
MFCD12024333
SY117424
DTXSID40443477
6-Benzyloxy-3,4-dihydro-2H-naphthalen-1-one
DS-7083
6-Benzyloxy-1-tetralone
6-(benzyloxy)-3,4-dihydronaphtalen-1(2H)-one
BDBM50017423
6-(Benzyloxy)-3,4-dihydronaphthalen-1(2H)-one
3,4-Dihydro-6-(phenylmethoxy)-1(2H)-naphthalenone
6-(Benzyloxy)-3,4-dihydrophthalen-1(2H)-one
AK132599

MDL Number

MFCD12024333

FAQ

What are the physical and chemical properties of 6-(Benzyloxy)-3,4-dihydro-1(2H)-naphthalenone (CAS: 32263-70-0)?

6-(Benzyloxy)-3,4-dihydro-1(2H)-naphthalenone (CAS: 32263-70-0) is a crystalline solid with a molecular weight of approximately 245.26 g/mol. It has a low water solubility, with a solubility of about 0.5 g/L at 25°C. The compound is moderately reactive, showing some sensitivity to acid and base conditions. It is insoluble in water but soluble in organic solvents like methanol and dichloromethane.

How is 6-(Benzyloxy)-3,4-dihydro-1(2H)-naphthalenone (CAS: 32263-70-0) typically synthesized?

6-(Benzyloxy)-3,4-dihydro-1(2H)-naphthalenone can be synthesized via the Swern oxidation of 6-benzyloxy-1,2,3,4-tetrahydroisoquinoline. The reaction requires acetic anhydride and dimethyl sulfoxide (DMSO) as the oxidant, with yields typically around 70-80%. The reaction is conducted with careful monitoring of temperature and time to ensure the desired product is formed.

What industries use 6-(Benzyloxy)-3,4-dihydro-1(2H)-naphthalenone (CAS: 32263-70-0)?

6-(Benzyloxy)-3,4-dihydro-1(2H)-naphthalenone (CAS: 32263-70-0) is primarily used in the pharmaceutical industry for the synthesis of various bioactive compounds. It also finds applications in the polymer industry as a monomer. Additionally, this compound can be used in the development of sensors due to its chemical reactivity and stability.

What precautions should be taken when handling 6-(Benzyloxy)-3,4-dihydro-1(2H)-naphthalenone (CAS: 32263-70-0)?

When handling 6-(Benzyloxy)-3,4-dihydro-1(2H)-naphthalenone (CAS: 32263-70-0), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and moisture. In case of spill, it is recommended to use a fume hood and clean up with appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.