1,2-Difluoro-4-(trifluoromethyl)benzene

Basic Information

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CAS Number

32137-19-2

Molecular Formula

C7H3F5

Molecular Weight

182.09 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

102°C

Flash Point

103-104°C

Refractive Index

1.388-1.392

SMILES

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C1=CC(=C(C=C1C(F)(F)F)F)F

InChI

InChI=1S/C7H3F5/c8-5-2-1-4(3-6(5)9)7(10,11)12/h1-3H

InChIKey

MVCGQTYWLZSKSB-UHFFFAOYSA-N

LogP

2.9836

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

152

Safety Information

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GHS Hazard Pictograms

H226

H315

H319

H335

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 3 Class 3

Synonyms & References

English

CS-W017133
SCHEMBL2147584
MFCD00077510
1,2-Difluoro-4-(trifluoromethyl)benzene #
EN300-27265
A5784
D3370
1,2-Difluoro-4-(trifluoromethyl)benzene
NS00123602
(R)-3,4-DIHYDROXY-BUTYRICACIDMETHYLESTER
AKOS005063452
32137-19-2
FT-0614282
Benzene, 1,2-difluoro-4-(trifluoromethyl)-
3,4-Difluorobenzotrifluoride
2,4-Difluoro-1-trifluoromethyl-benzene;3,4-Difluorobenzotrifluoride
PS-11685
SY032395
AM61465
DTXSID80345229
alpha,alpha,alpha,3,4-Pentafluorotoluene
ALPHA,ALPHA,ALPHA,3,4-PENTAFLUOROTOLUENE
1,2-DIFLUORO-4-TRIFLUOROMETHYL-BENZENE
à,à,à,3,4-pentafluorotoluene
3,4-Difluorobenztrifluoride
1,2-Difluor-4-trifluormethylbenzol
1,2-difluoro-4-trifluoromethylbenzene
3,4-difluoro-benzotrifluoride
3,4-Difluoro-trifluoromethylbenzene
Benzene,1,2-difluoro-4-(trifluoromethyl)
α,α,α,3,4-Pentafluorotoluene

MDL Number

MFCD00077510

Customs Code

2903999090

FAQ

What are the physical and chemical properties of 1,2-Difluoro-4-(trifluoromethyl)benzene (CAS: 32137-19-2)?

1,2-Difluoro-4-(trifluoromethyl)benzene is a colorless, crystalline solid with a molecular weight of 252.11 g/mol. It has low water solubility but is soluble in common organic solvents like dichloromethane and acetonitrile. The compound is relatively stable but can undergo halogenation reactions under certain conditions. It has a high boiling point of around 200°C and a melting point of 58-59°C.

How is 1,2-Difluoro-4-(trifluoromethyl)benzene (CAS: 32137-19-2) typically synthesized?

1,2-Difluoro-4-(trifluoromethyl)benzene is typically synthesized via fluorination of 4-(trifluoromethyl)benzene with hydrogen fluoride in the presence of a Lewis acid catalyst. The reaction is selective and yields the desired compound with good efficiency. The process requires careful control of reaction conditions to achieve high yield and purity.

What industries use 1,2-Difluoro-4-(trifluoromethyl)benzene (CAS: 32137-19-2)?

1,2-Difluoro-4-(trifluoromethyl)benzene is used in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry for the production of advanced materials, and in the semiconductor industry for manufacturing electronic components. It is also utilized in the chemical sensor field for detecting various compounds.

What precautions should be taken when handling 1,2-Difluoro-4-(trifluoromethyl)benzene (CAS: 32137-19-2)?

1,2-Difluoro-4-(trifluoromethyl)benzene should be handled in a well-ventilated area or a fume hood due to its flammability. Protective equipment such as gloves, goggles, and a lab coat are essential. Spills should be cleaned up using appropriate absorbents and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.