1-Amino-2-methylpropane-2-thiol

Basic Information

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CAS Number

32047-53-3

Molecular Formula

C4H12ClNS

Molecular Weight

141.66 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

SMILES

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CC(C)(CN)S.Cl

InChI

InChI=1S/C4H11NS.ClH/c1-4(2,6)3-5;/h6H,3,5H2,1-2H3;1H

InChIKey

YZCAFAKJYGDMSY-UHFFFAOYSA-N

LogP

1.0752999999999997

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

42.8

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

A857478
AKOS005137923
1-amino-2-methylpropane-2-thiol;hydrochloride
32047-53-3
NSC 254029
1-Amino-2-methyl-2-propanethiol hydrochloride
1-amino-2-methylpropan2-thiol hydrochloride
EC 434-480-1
2-Propanethiol, 1-amino-2-methyl-, hydrochloride
SB75661
BCP10543
J-520369
2-mercapto-2-methyl-1-propylamine hydrochloride
2-Methyl-2-thiopropylamine Hydrochloride
Dimethylcysteamine HCl
NSC254029
1-Amino-2-methyl-2-propanethiol hydrochloride, 97%
DTXSID10953917
SCHEMBL1880943
YZCAFAKJYGDMSY-UHFFFAOYSA-N
1-amino-2-methylpropane-2-thiol hydrochloride
MFCD00191744
GS-0908
1-Amino-2-methylpropane-2-thiol--hydrogen chloride (1/1)
FT-0601930
NSC-254029
DIMETHYLCYSTEAMINE HYDROCHLORIDE
1-Amino-2-methyl-2-propanethiol HCl
1-amino-2-methyl-2-propanethiol hydro-chloride
CS-0140693
1-Amino-2-methylpropane-2-thiol

MDL Number

MFCD00191744

Customs Code

2930909090

FAQ

What are the physical and chemical properties of 1-Amino-2-methylpropane-2-thiol (CAS: 32047-53-3)?

1-Amino-2-methylpropane-2-thiol is a colorless liquid at room temperature. It has a molecular weight of approximately 121.18 g/mol. This compound is slightly soluble in water but miscible with organic solvents. It is thermally stable but can react with strong oxidizing agents and bases. It is also known for its reactivity towards nucleophiles and electrophiles in chemical reactions.

How is 1-Amino-2-methylpropane-2-thiol (CAS: 32047-53-3) typically synthesized?

1-Amino-2-methylpropane-2-thiol is usually synthesized via the reaction between 2-methylthioacetaldehyde and ammonia. This process involves the nucleophilic addition of ammonia to the aldehyde group of the 2-methylthioacetaldehyde. Commonly used solvents include dimethylformamide (DMF) and ethanol. The yield is typically around 80-85%, and the reaction is carried out under mild basic conditions.

What industries use 1-Amino-2-methylpropane-2-thiol (CAS: 32047-53-3)?

1-Amino-2-methylpropane-2-thiol is utilized in various industries. It is a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antifungal and antibacterial agents. It also finds applications in the polymer industry as a curing agent, in the production of sensors, and in the semiconductor industry for its use in etching solutions and surface treatments.

What precautions should be taken when handling 1-Amino-2-methylpropane-2-thiol (CAS: 32047-53-3)?

When handling 1-Amino-2-methylpropane-2-thiol, safety precautions are essential. Always wear personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be contained and cleaned up with appropriate absorbents. In case of contact with skin or eyes, immediately flush with copious amounts of water. Refer to the Safety Data Sheet (SDS) for detailed emergency response procedures and storage guidelines.