POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT

Basic Information

View in Editor

CAS Number

31852-29-6

Molecular Formula

C19H27KN7O16P2

Molecular Weight

710.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Insecticides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Solubility

Soluble in DMSO; H2O : 10mg/mL

SMILES

View in Editor

C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)(O)O)O)O.[K]

InChI

InChI=1S/C10H13N4O8P.C9H14N3O8P.K/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20);1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);

InChIKey

KHPUABRWHJGXNJ-UHFFFAOYSA-N

LogP

-4.978699999999992

Topological Polar Surface Area

357.38000000000005 Å²

Hydrogen Bond Donor/Acceptor

11 / 23

Complexity

1090

Synonyms & References

English

PolyI：C-K
POLY[I] POLY[C] POTASSIUM SALT
POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT
Polyinosinic acid . Polycytidylic acid potassium salt
polyinosinic-polycytidylic acid*potassium
polyinosinic acid/ polycytidylic potassium
Poly I：C PotassiuM Salt
5'-Cytidylic acid homopolymer complex with 5'-inosinic acid homopolyme potassium salt
5'-Inosinic acid,homopolymer, complex with 5'-cytidylic acid homopolymer (1:1), potassium salt
Polyinosinic-polycytidylic Acid (potassium salt)
POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM
Poly I:C Potassium Salt
Polyinosinic-cytidylic potassium salt
Polyinosinic-Polycytidylic Acid Potassium Salt
Poly (I:C)
Poly(I) • Poly(C)
5'-Cytidylic acid polymers complex with 5'-inosinic acid polymers potassium salt
Inosinic acid-cytidylic acid polymer complex potassium salt
Poly I-poly C potassium salt
PolyinosinicCpolycytidylic acid potassium salt
CID 137031716

MDL Number

MFCD00131983

FAQ

What are the physical and chemical properties of POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT (CAS: 31852-29-6)?

Polyinosinic-polycytidylic acid potassium salt is a nucleic acid derivative with a high molecular weight. It is a white to off-white crystalline solid. The compound is soluble in water but insoluble in organic solvents. It exhibits limited reactivity in aqueous solutions, primarily undergoing hydrolysis. It is stable under neutral and slightly acidic conditions but can degrade under basic conditions.

How is POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT (CAS: 31852-29-6) typically synthesized?

POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT is synthesized by condensation of inosine monophosphate and cytidine monophosphate followed by potassium salt formation. Commonly, this is achieved through enzymatic or chemical methods. The process involves controlled polymerization and subsequent neutralization with potassium hydroxide. The yield and selectivity are typically high, with good reproducibility.

What industries use POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT (CAS: 31852-29-6)?

POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT is used in the pharmaceutical industry for vaccine adjuvants and antiviral drugs. It is also utilized in the biotechnology sector for gene therapy and as a sensor material in biosensors. Additionally, it has applications in the semiconductor industry for certain types of molecular electronics.

What precautions should be taken when handling POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT (CAS: 31852-29-6)?

When handling POLYINOSINIC-POLYCYTIDYLIC ACID POTASSIUM SALT, proper personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be handled with caution using absorbent materials and appropriate waste disposal procedures. Always refer to the Safety Data Sheet (SDS) for detailed safety guidelines.