2-Bromo-1-fluoronaphthalene

Basic Information

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CAS Number

317-79-3

Molecular Formula

C10H6BrF

Molecular Weight

225.06 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

282.8ºC at 760 mmHg

Density

1.563

Flash Point

128.4ºC

Refractive Index

1.638

SMILES

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C1=CC=C2C(=C1)C=CC(=C2F)Br

InChI

InChI=1S/C10H6BrF/c11-9-6-5-7-3-1-2-4-8(7)10(9)12/h1-6H

InChIKey

WPNSUUQOEPQDOI-UHFFFAOYSA-N

LogP

3.7414000000000014

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

160

Synonyms & References

English

CS-0217783
AC-2362
MFCD09864690
Naphthalene, 2-bromo-1-fluoro-
SCHEMBL1248560
EN300-84603
AKOS022172027
AS-40912
FT-0646119
A820985
J-508177
DTXSID60660306
317-79-3
2-BROMO-1-FLUORONAPHTHALENE
SY128125
2-Bromo-1-fluoronaphthalene
1-Fluor-2-bromnaphthalin
2-Brom-1-fluor-naphthalin
2-Bromo-1-fluoro-naphthalene
Naphthalene,2-bromo-1-fluoro

MDL Number

MFCD09864690

Customs Code

2903999090

FAQ

What are the physical and chemical properties of 2-Bromo-1-fluoronaphthalene (CAS: 317-79-3)?

2-Bromo-1-fluoronaphthalene is a crystalline solid with a molecular weight of approximately 265.03 g/mol. It has a low solubility in water but is soluble in organic solvents like dichloromethane and acetone. Chemically, it reacts readily with nucleophiles and can undergo substitution reactions. It is less reactive than some other halogen-substituted derivatives but exhibits significant aromaticity.

How is 2-Bromo-1-fluoronaphthalene (CAS: 317-79-3) typically synthesized?

2-Bromo-1-fluoronaphthalene is typically synthesized via bromination of 1-fluoronaphthalene using bromine in the presence of a Lewis acid catalyst like aluminum bromide. The reaction involves electrophilic aromatic substitution, leading to a high yield and good selectivity. The process is conducted under anhydrous conditions to prevent side reactions.

What industries use 2-Bromo-1-fluoronaphthalene (CAS: 317-79-3)?

2-Bromo-1-fluoronaphthalene is primarily used in the pharmaceutical industry for the synthesis of intermediates and potential drug candidates. It also finds applications in the polymer industry for producing specialty polymers. Additionally, it is used in the development of sensors and semiconductors due to its unique electronic properties.

What precautions should be taken when handling 2-Bromo-1-fluoronaphthalene (CAS: 317-79-3)?

When handling 2-Bromo-1-fluoronaphthalene, it is crucial to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be immediately cleaned up with appropriate absorbents, and the material should be disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.