Allopurinol | CAS No. 315-30-0

Allopurinol

Basic Information

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CAS Number

315-30-0

Molecular Formula

C5H4N4O

Molecular Weight

136.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

Powder

Melting Point

>300 °C

Boiling Point

423.2°C at 760 mmHg

Water Solubility

0.35 g/L (25 ºC)

Flash Point

129.7 °C

Solubility

1 M NaOH: soluble50mg/mL, clear to very slightly hazy, colorless to faintly yellow

Refractive Index

1.8500 (estimate)

SMILES

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O=c1nc[nH]c2[nH]ncc12

InChI

InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)

InChIKey

OFCNXPDARWKPPY-UHFFFAOYSA-N

LogP

-0.35380000000000006

pKa

10.2(at 25℃)

Topological Polar Surface Area

74.43 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

275

Safety Information

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GHS Hazard Pictograms

H301

H317

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H317 May cause an allergic skin reaction
Sensitization, Skin

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

1H-Pyrazolo[3,4-d]pyrimidin-4(5H)-one
Allopurinol
Hydroxypyrazolodpyrimidine
pyrazolo(3,4-d)pyrimidin-1-ol
4-Hydroxypyrazolo(3,4-d)-pyrimidine
1H-Pyrazolo[3,4-d]pyrimidin-4-ol
ACO
ALLOPURINOL(P)
ALLOPURINOL(RG)
1H-Pyrazolo(3,4-d)pyrimidin-4-ol (4-Hydroxypyrazolo(3,4-d)pyrimidine
4-HPP
4-Hydroxypyrazolo[3,4-d]pyrimidine
AL-100
allopurinal
aloral
Anzief
Apurin
Apurol
HPP
Pural
Remid
Urbol
1H-Pyrazolo(3,4-d)pyrimidin-4-ol
4-Hydroxypyrazolo(3,4-d)pyrimidine
HPP；Allopurinol
1H-pyrazolo[3,4-d]pyrimidin-4-ol
1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one

MDL Number

MFCD00599413

Customs Code

2933990090

FAQ

What is Allopurinol (CAS: 315-30-0)?

Allopurinol (CAS: 315-30-0) is a purine analog used primarily as a medication. Its chemical formula is C5H4N4O. It is a white crystalline powder with a bitter taste, and it is soluble in water. Allopurinol is known for its ability to inhibit xanthine oxidase, an enzyme involved in uric acid production.

What are the main uses of Allopurinol (CAS: 315-30-0)?

Allopurinol (CAS: 315-30-0) is mainly used in the treatment of gout and hyperuricemia by reducing uric acid levels. It is also employed in the management of certain types of kidney stones and as a chemopreventive agent in patients with chronic kidney disease. Additionally, it has applications in research for studying purine metabolism and enzyme inhibition.

Is Allopurinol (CAS: 315-30-0) safe?

Allopurinol (CAS: 315-30-0) is generally considered safe when used as directed, but it may cause side effects such as rash, gastrointestinal discomfort, and, in rare cases, severe allergic reactions. It is important to follow safety guidelines and consult a healthcare professional before use. Proper handling and storage are also essential to ensure its safety and efficacy.

How should Allopurinol (CAS: 315-30-0) be stored?

Allopurinol (CAS: 315-30-0) should be stored in a cool, dry place away from direct light. It is typically kept in a sealed container at a temperature of 15-30°C. Maintaining proper humidity levels is crucial to prevent degradation, and it should be protected from moisture and air exposure to preserve its stability and potency.