N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide

Basic Information

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CAS Number

313553-47-8

Molecular Formula

C18H16N2OS

Molecular Weight

308.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Solubility

Insuluble (2.8E-4 g/L) (25 ºC),

SMILES

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CC1=CC(=C(C=C1)C2=CSC(=N2)NC(=O)C3=CC=CC=C3)C

InChI

InChI=1S/C18H16N2OS/c1-12-8-9-15(13(2)10-12)16-11-22-18(19-16)20-17(21)14-6-4-3-5-7-14/h3-11H,1-2H3,(H,19,20,21)

InChIKey

JPMOKRWIYQGMJL-UHFFFAOYSA-N

LogP

4.679240000000003

Topological Polar Surface Area

41.99 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

383

Synonyms & References

English

N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]benzamide
IBT 13131
INH1
N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]benzamidehydrochloride
N-[4-(2,4-dimethylphenyl)thiazol-2-yl]benzamide
SCHEMBL18874412
s7493
HMS3653F09
N-(4-(2,4-dimethylphenyl)thiazol-2-yl)benzamide
Oprea1_380163
SW219216-1
AM85716
Benzamide,N-[4-(2,4-dimethylphenyl)-2-thiazolyl]-
HY-16660
CS-3155
EX-A514
N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide
AC-33047
MFCD01356769
SB19451
BCP06473
BS-16493
CID 959043
AKOS000448630
N-(4-(2,4-dimethylphenyl) -2-thiazolyl)benzamide
Hec1/Nek2 Mitotic Pathway Inhibitor I, INH1
Q18350699
313553-47-8
CHEMBL471411
CCG-267565
SCHEMBL2753844

MDL Number

MFCD01356769

FAQ

What are the physical and chemical properties of N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide (CAS: 313553-47-8)?

N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide is a crystalline solid with a molecular weight of approximately 353.39 g/mol. It is slightly soluble in water and ethanol, and more soluble in organic solvents like DMSO. The compound is moderately stable under normal conditions but can react with strong bases to form the corresponding salt. It is non-flammable and has a low vapor pressure.

How is N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide (CAS: 313553-47-8) typically synthesized?

N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide is typically synthesized via a multi-step process involving the condensation of a 1,3-thiazole derivative and a benzoyl chloride. The synthesis involves the use of a suitable catalyst and requires careful control of reaction conditions to achieve high yield and selectivity. The process is commonly carried out in a solvent such as dichloromethane or dimethylformamide.

What industries use N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide (CAS: 313553-47-8)?

N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide is used in the pharmaceutical industry for its potential as an antifungal and anti-inflammatory agent. It also finds applications in the polymer industry for enhancing the properties of polymers. Additionally, it is explored in the field of sensor technology for its sensitivity to certain chemical compounds and in semiconductor manufacturing for its potential use in thin film deposition processes.

What precautions should be taken when handling N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide (CAS: 313553-47-8)?

When handling N-[4-(2,4-dimethylphenyl)-1,3-thiazol-2-yl]benzamide, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. The substance should be used in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up promptly using appropriate absorbents, and the area should be well-ventilated. Always consult the Material Safety Data Sheet (MSDS) for specific safety guidelines and emergency procedures.