(2R)-2-Piperazinecarboxylic acid

Basic Information

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CAS Number

31321-68-3

Molecular Formula

C5H10N2O2

Molecular Weight

130.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

171 C

Boiling Point

67 C

SMILES

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C1CNC(CN1)C(=O)O

InChI

InChI=1S/C5H10N2O2/c8-5(9)4-3-6-1-2-7-4/h4,6-7H,1-3H2,(H,8,9)/t4-/m1/s1

InChIKey

JSSXHAMIXJGYCS-SCSAIBSYSA-N

LogP

-1.3675999999999995

Topological Polar Surface Area

61.36 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

116

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

C19780
(r)-2-carboxypiperazine
Q27124253
(R)-Piperazine-2-carboxylic acid
(R)-2-Piperazinecarboxylate
(R)-piperazine-2-carboxylate
A5674
MFCD01318683
AC-2976
JSSXHAMIXJGYCS-SCSAIBSYSA-N
CHEMBL1229073
31321-68-3
Piperazine-2-carboxylic acid;(R)-PIPERAZINE-2-CARBOXYLIC ACID
CHEBI:55357
(R)-Piperazine-2-carboxylicacid
AKOS015854364
(2R)-piperazine-2-carboxylic acid
AM81366
2-Piperazinecarboxylic acid, (2R)-
EN300-132437
SCHEMBL172309
(R)-piperazine-2-carboxylic acid, AldrichCPR
BP-11112
(R)-Piperazine-2-carboxylic acid Hydrochloride
(R)-(+)-PIPERAZINE-2-CARBOXYLIC ACID
(R)-(+)-PIPERAZINE-2-CARBOXYLIC ACID. 2HCL
(R)-2-Piperazinecarboxylic Acid
R-PCA
2-Piperazinecarboxylicacid, (R)-
R-Piperazine-2-carboxylic acid

MDL Number

MFCD01318683

Customs Code

2933599090

FAQ

What are the physical and chemical properties of (2R)-2-Piperazinecarboxylic acid (CAS: 31321-68-3)?

(2R)-2-Piperazinecarboxylic acid is a white crystalline solid with a molecular weight of approximately 135.14 g/mol. It has a pKa of about 6.2 and is slightly soluble in water. This compound is known for its basic nature and is reactive towards acids, forming salts. It is often used in chemical synthesis and research due to its unique structure.

How is (2R)-2-Piperazinecarboxylic acid (CAS: 31321-68-3) typically synthesized?

(2R)-2-Piperazinecarboxylic acid is synthesized from 2-amino-2-piperidinecarboxylic acid through a process involving hydrogenation or via a condensation reaction with appropriate reagents. Commonly, this acid is produced in multi-step syntheses with good yields and reproducibility, often requiring suitable catalysts and reaction conditions to achieve high purity.

What industries use (2R)-2-Piperazinecarboxylic acid (CAS: 31321-68-3)?

(2R)-2-Piperazinecarboxylic acid is widely used in the pharmaceutical industry for the development of drug intermediates and in polymer chemistry for the synthesis of functional polymers. It is also utilized in sensor technology and semiconductor manufacturing due to its unique chemical properties.

What precautions should be taken when handling (2R)-2-Piperazinecarboxylic acid (CAS: 31321-68-3)?

When handling (2R)-2-Piperazinecarboxylic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage information.