NEUROMEDIN U-25 (HUMAN)

Basic Information

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CAS Number

312306-89-1

Molecular Formula

C70H152N31O6

Molecular Weight

1524.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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OC[C@H](NC[C@H](CCC(=O)N)NC[C@@H](NC[CH]NC[CH]NC[C@@H]1CCCN1C[C@@H](NC[C@H](CCC(=O)N)NC)CO)CO)CN[C@@H](CCCNC(=N)N)CNCCN[CH]CN[CH]CN[C@@H](CC(C)C)CN[CH]CN[C@H](CN1CCC[C@H]1CN[C@H](CN[C@@H](CC(=O)N)CN)CCCNC(=N)N)CCCNC(=N)N

InChI

InChI=1S/C70H152N31O6/c1-52(2)35-59(39-86-29-32-88-57(11-6-20-93-70(79)80)47-100-33-8-13-64(100)46-99-55(10-5-19-92-69(77)78)41-96-58(37-71)36-67(74)107)89-30-27-83-22-21-82-23-25-85-38-54(9-4-18-91-68(75)76)94-44-61(50-103)97-42-56(15-17-66(73)106)95-43-60(49-102)90-31-28-84-24-26-87-45-63-12-7-34-101(63)48-62(51-104)98-40-53(81-3)14-16-65(72)105/h21,26-29,52-64,81-90,94-99,102-104H,4-20,22-25,30-51,71H2,1-3H3,(H2,72,105)(H2,73,106)(H2,74,107)(H4,75,76,91)(H4,77,78,92)(H4,79,80,93)/t53-,54-,55-,56-,57-,58-,59-,60+,61+,62+,63-,64-/m0/s1

InChIKey

NUKVYVDZMDTREJ-FHUAGPRDSA-N

LogP

-8.34853999999988

Topological Polar Surface Area

600.6399999999996 Å²

Hydrogen Bond Donor/Acceptor

39 / 37

Complexity

2270

Synonyms & References

English

L-Aspartamide,L-phenylalanyl-L-arginyl-L-valyl-L-a-aspartyl-L-a-glutamyl-L-a-glutamyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-prolyl-L-phenylalanyl-L-alanyl-L-seryl-L-glutaminyl-L-seryl-L-arginylglycyl-L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-
GLY-ASN-HIS-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2: GNHWAVGHLM-NH2
H-PHE-ARG-VAL-ASP-GLU-GLU-PHE-GLN-SER-PRO-PHE-ALA-SER-GLN-SER-ARG-GLY-TYR-PHE-LEU-PHE-ARG-PRO-ARG-ASN-NH2
L-Aspartamide,L-phenylalanyl-L-arginyl-L-valyl-L-a-aspartyl-L-a-glutamyl-L-a-glutamyl-L-phenyl...
L-Aspartamide,L-phenylalanyl-L-arginyl-L-valyl-L-a-aspartyl-L-a-glutamyl-L-a-glutamyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-p
Neuromedin U-25 (human) ,NMU-25 (human)
Neuromedin U-25 (human)

FAQ

What are the physical and chemical properties of NEUROMEDIN U-25 (HUMAN) (CAS: 312306-89-1)?

NEUROMEDIN U-25 (HUMAN) is a peptide with a molecular weight of approximately 2500 Da. It is soluble in water and is stable under standard laboratory conditions. The compound typically exists as a crystalline form, making it easy to purify. It is reactive towards proteases and should be stored in an appropriate buffer to minimize degradation.

How is NEUROMEDIN U-25 (HUMAN) (CAS: 312306-89-1) typically synthesized?

NEUROMEDIN U-25 (HUMAN) is typically synthesized using solid-phase peptide synthesis (SPPS) techniques. The synthesis involves the stepwise addition of amino acids to a solid support, followed by cleavage from the support and purification. Commonly, Boc-protected amino acids are used, and the final peptide is deprotected and cleaved from the resin under strong basic conditions. The yield from such synthesis can range from 50% to 90%.

What industries use NEUROMEDIN U-25 (HUMAN) (CAS: 312306-89-1)?

NEUROMEDIN U-25 (HUMAN) is primarily used in the pharmaceutical and biotechnology industries for its potential as a therapeutic agent. It is also used in research for studying biological functions and signaling pathways. Additionally, it may have applications in the development of biosensors and as a research tool in neuroscience.

What precautions should be taken when handling NEUROMEDIN U-25 (HUMAN) (CAS: 312306-89-1)?

When handling NEUROMEDIN U-25 (HUMAN), it is crucial to use appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up carefully using appropriate absorbent materials, and the area should be decontaminated. Always refer to the safety data sheet (SDS) for detailed handling instructions and emergency procedures.