![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
4,4,5,5-Tetramethyl-2-(2-methyl-1-naphthyl)-1,3,2-dioxaborolane | CAS No. 312303-48-3
4,4,5,5-Tetramethyl-2-(2-methyl-1-naphthyl)-1,3,2-dioxaborolane
Basic Information
CAS Number
312303-48-3
Molecular Formula
C17H21BO2
Molecular Weight
268.16 g/mol
AD
Basic Physical Properties
Boiling Point
395.7±21.0℃ at 760 mmHg
Synonyms & References
English
- 4,4,5,5-tetramethyl-2-(2-methyl-1-naphthalenyl)-1,3,2-Dioxaborolane
- 2-Methylnaphthalene-1-boronic Acid Pinacol Ester
- 4,4,5,5-tetramethyl-2-(2-methylnaphthalen-1-yl)-1,3,2-dioxaborolane
MDL Number
MFCD22189526
FAQ
What are the physical and chemical properties of 4,4,5,5-Tetramethyl-2-(2-methyl-1-naphthyl)-1,3,2-dioxaborolane (CAS: 312303-48-3)?
4,4,5,5-Tetramethyl-2-(2-methyl-1-naphthyl)-1,3,2-dioxaborolane is a white crystalline solid with a molecular weight of approximately 294.34 g/mol. It has a low solubility in water but is soluble in common organic solvents like dichloromethane and toluene. The compound is known for its high reactivity in boron-catalyzed reactions, particularly in Suzuki coupling reactions.
How is 4,4,5,5-Tetramethyl-2-(2-methyl-1-naphthyl)-1,3,2-dioxaborolane (CAS: 312303-48-3) typically synthesized?
4,4,5,5-Tetramethyl-2-(2-methyl-1-naphthyl)-1,3,2-dioxaborolane is typically synthesized through a multistep process involving the formation of a naphthyl boronic acid, followed by its conversion to the dioxaborolane derivative. This process requires the use of boronic acids, phenol derivatives, and catalysts such as Pd(0) complexes. The yield of the product is around 70-80%.
What industries use 4,4,5,5-Tetramethyl-2-(2-methyl-1-naphthyl)-1,3,2-dioxaborolane (CAS: 312303-48-3)?
4,4,5,5-Tetramethyl-2-(2-methyl-1-naphthyl)-1,3,2-dioxaborolane is primarily used in the pharmaceutical and polymer industries. It serves as a key intermediate in the synthesis of various biologically active compounds and is also utilized in the development of novel materials with specific properties.
What precautions should be taken when handling 4,4,5,5-Tetramethyl-2-(2-methyl-1-naphthyl)-1,3,2-dioxaborolane (CAS: 312303-48-3)?
When handling 4,4,5,5-Tetramethyl-2-(2-methyl-1-naphthyl)-1,3,2-dioxaborolane, it is essential to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound should be stored in a cool, well-ventilated area, and fume hoods should be used during its manipulation. In case of spill, it should be cleaned up carefully, and the SDS (Safety Data Sheet) should be consulted for detailed guidelines.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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