Ethyl (dimethoxyphosphoryl)acetate

Basic Information

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CAS Number

311-46-6

Molecular Formula

C6H13O5P

Molecular Weight

196.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Melting Point

Not available

Boiling Point

135°C/10mmHg

Refractive Index

n20/D 1.435(lit.)<br />n20/D 1.435

Vapor Pressure

0.0±0.5 mmHg at 25°C

SMILES

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CCOC(=O)CP(=O)(OC)OC

InChI

InChI=1S/C6H13O5P/c1-4-11-6(7)5-12(8,9-2)10-3/h4-5H2,1-3H3

InChIKey

HUNISAHOCCASGM-UHFFFAOYSA-N

LogP

1.0354

Topological Polar Surface Area

61.830000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 5

Complexity

182

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

HUNISAHOCCASGM-UHFFFAOYSA-
CS-W022647
Ethyl dimethylphosphonoacetate, technical, >=90% (GC)
ethyl dimethyl phosphonoacetate
SY006735
Ethyl (dimethoxyphosphoryl)acetate
ethyl(dimethylphosphono)acetate
ethyl 2-dimethoxyphosphorylacetate
ethyl [bis(methyloxy)phosphoryl]acetate
Acetic acid, 2-(dimethoxyphosphinyl)-, ethyl ester
NS00029028
SCHEMBL639641
E1160
Ethyl (dimethoxyphosphinoyl)acetate
DIMETHYL(ETHOXYCARBONYLMETHYL)PHOSPHONATE
311-46-6
FT-0631932
Acetic acid, (dimethoxyphosphinyl)-, ethyl ester
AMY3931
HUNISAHOCCASGM-UHFFFAOYSA-N
ethyl 2-(dimethoxyphosphoryl)acetate
W-106914
Dimethylphosphonoacetic Acid Ethyl Ester
A876017
AKOS015899895
AS-15164
MFCD00015677
BCP24421
InChI=1/C6H13O5P/c1-4-11-6(7)5-12(8,9-2)10-3/h4-5H2,1-3H3
Ethyl dimethylphosphonoacetate
DTXSID00185043

MDL Number

MFCD00015677

Customs Code

2931900090

FAQ

What are the physical and chemical properties of Ethyl (dimethoxyphosphoryl)acetate (CAS: 311-46-6)?

Ethyl (dimethoxyphosphoryl)acetate (CAS: 311-46-6) is a colorless to slightly yellow liquid with a molecular weight of 194.16 g/mol. It has a low solubility in water but is soluble in organic solvents. The compound is known for its high reactivity, particularly in nucleophilic substitution reactions.

How is Ethyl (dimethoxyphosphoryl)acetate (CAS: 311-46-6) typically synthesized?

Ethyl (dimethoxyphosphoryl)acetate is typically synthesized through the reaction of dimethoxyphosphoryl chloride with ethyl acetate in the presence of a base like sodium hydride. The process involves careful control of temperature and reaction time to achieve high yields and selectivity.

What industries use Ethyl (dimethoxyphosphoryl)acetate (CAS: 311-46-6)?

Ethyl (dimethoxyphosphoryl)acetate (CAS: 311-46-6) finds applications in the pharmaceutical industry for drug synthesis, as a reagent in organic synthesis, and in the semiconductor industry for chemical vapor deposition processes. It is also used in certain polymer synthesis and as a reaction intermediate.

What precautions should be taken when handling Ethyl (dimethoxyphosphoryl)acetate (CAS: 311-46-6)?

When handling Ethyl (dimethoxyphosphoryl)acetate (CAS: 311-46-6), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Use a fume hood during manipulation to avoid inhalation. Store the compound in a cool, dry place, away from sources of heat and ignition. In case of a spill, use appropriate cleanup procedures and consult the Material Safety Data Sheet (MSDS) for detailed instructions.