(2S)-piperidine-2-carboxylic acid

Basic Information

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CAS Number

3105-95-1

Molecular Formula

C6H11NO2

Molecular Weight

129.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

272 °C

Boiling Point

265.8°C at 760 mmHg

Flash Point

114.5℃

Refractive Index

-27 ° (C=4, H2O)

Specific Rotation

-27.5 º (c=5, H2O 24 ºC)

SMILES

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OC(=O)[C@@H]1CCCCN1

InChI

InChI=1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)/t5-/m0/s1

InChIKey

HXEACLLIILLPRG-YFKPBYRVSA-N

LogP

0.21310000000000012

pKa

2.28(at 25℃)

Topological Polar Surface Area

49.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

114

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(S)-Piperidine-2-carboxylic acid
l(-)-pipecolinic acid
(s)-(-)-2-piperidinecarboxylic acid
L-HOMOPROLINE
L-Pipecolinic acid
L-Pipecolic acid
H-HoPro-OH
H-Homopro-OH
L-2-Pipecolinic acid
Pipecolic acid, (S)-(-)-
S-(-)-Pipecolinic acid
: L(-)-Pipecolinic acid
(-)-(S)-pipecolic acid
H-L-PIP-OH
HOMOPROLINE
H-PIC(2)-OH
h-pip-oh
L-HOMOPRO
L-PIPECOLATE
PIP-OH
(S)-(−)-2-Piperidinecarboxylic acid
L-Homoproline
H-L-Pip-OH
L-Pipecolinic Acid
(S)-(-)-2-Piperidinecarboxylic Acid
(S)-(-)-2-Piperidinecarboxylic acid
(2S)-piperidine-2-carboxylic acid

MDL Number

MFCD00005981

FAQ

What is (2S)-piperidine-2-carboxylic acid (CAS: 3105-95-1)?

(2S)-Piperidine-2-carboxylic acid (CAS: 3105-95-1) is a chiral organic compound with the chemical formula C6H11NO2. It features a piperidine ring substituted with a carboxylic acid group at the 2nd position and exhibits specific stereochemical properties. This compound is commonly used as an intermediate in organic synthesis due to its versatile functional groups and structural characteristics.

What are the main uses of (2S)-piperidine-2-carboxylic acid (CAS: 3105-95-1)?

(2S)-Piperidine-2-carboxylic acid (CAS: 3105-95-1) is widely utilized in pharmaceutical research for developing drugs targeting neurological and metabolic disorders. It also serves as a key component in the synthesis of various chemical compounds, including agrochemicals and specialty polymers. Its applications span medicinal chemistry, industrial processes, and academic studies due to its reactivity and structural adaptability.

Is (2S)-piperidine-2-carboxylic acid (CAS: 3105-95-1) safe?

(2S)-Piperidine-2-carboxylic acid (CAS: 3105-95-1) is generally considered safe when handled properly. However, it may cause mild irritation to the skin and eyes, and inhalation should be avoided. Safety data sheets recommend using appropriate protective equipment, such as gloves and goggles, and working in a well-ventilated area. It is classified under safety standards for chemical handling in laboratories and industries.

How should (2S)-piperidine-2-carboxylic acid (CAS: 3105-95-1) be stored?

(2S)-Piperidine-2-carboxylic acid (CAS: 3105-95-1) should be stored in a cool, dry, and dark place, ideally below 25°C, with humidity controlled under 60%. It requires airtight containers to prevent moisture absorption and degradation. Avoid exposure to light and ensure proper labeling to maintain stability and safety during storage.