Pargyline Hydrochloride

Basic Information

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CAS Number

306-07-0

Molecular Formula

C11H14ClN

Molecular Weight

149.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

160-163 °C

Boiling Point

228.4 ºC at 760 mmHg

Flash Point

83.9℃

SMILES

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CN(CC#C)CC1=CC=CC=C1.Cl

InChI

InChI=1S/C10H15N/c1-3-11(2)9-10-7-5-4-6-8-10/h4-8H,3,9H2,1-2H3

InChIKey

ABRGFZIXRKAUJS-UHFFFAOYSA-N

LogP

2.1383

Topological Polar Surface Area

3.24 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

159

Safety Information

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GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

Tox21_501022
N-Benzyl-N-methyl-2-propynylamine hydrochloride
Methylbenzylpropynylamine hydrochloride
N-methyl-N-(phenylmethyl)prop-2-yn-1-amine hydrochloride
PARGYLINE HYDROCHLORIDE [MART.]
NSC-757264
FT-0631924
s3690
Q27292421
PARGYLINE HYDROCHLORIDE [MI]
AMY20608
BCXCABRDBBWWGY-UHFFFAOYSA-N
Pargyline, HCl
N-benzyl-N-methylprop-2-yn-1-amine;hydrochloride
N-Methyl-N-propargylbenzylamineHydrochloride
EINECS 206-175-1
N-benzyl-N-methylprop-2-yn-1-amine hydrochloride
N-benzyl-N-methylprop-2-yn-1-amine hydrochloride; Eutonyl-ten; N-Methyl-N-propargylbenzylamine hydrochloride; Pargyline HCl
Pargyline hydrochloride (USAN:USP)
N-Methyl-N-propargylbenzylamine hydrochloride
USAF A-19120
A820454
A935225
4-(3-METHYLPYRAZIN-2-YL)-6-METHYL-PYRIMIDIN-2-AMINE
UNII-W70V6I2OMY
NCGC00256654-01
Pargyline hydrochloride
Pargyline HCl
NS00079435
AS-16929
P 8013

MDL Number

MFCD00012492

FAQ

What are the physical and chemical properties of Pargyline Hydrochloride (CAS: 306-07-0)?

Pargyline Hydrochloride (CAS: 306-07-0) is a white or off-white crystalline powder with a molecular weight of approximately 293.77 g/mol. It is sparingly soluble in water and alcohol, and soluble in dilute acids. Chemically, it is highly reactive towards bases and can undergo hydrolysis under basic conditions. It is insoluble in acetone and ether. Pargyline Hydrochloride is used as an intermediate in the synthesis of other pharmaceuticals and research reagents.

How is Pargyline Hydrochloride (CAS: 306-07-0) typically synthesized?

Pargyline Hydrochloride (CAS: 306-07-0) is typically synthesized through the reaction of pargyline with hydrochloric acid. The reaction involves the protonation of pargyline to form the hydrochloride salt. Commonly, this is achieved in an aqueous medium using hydrochloric acid as the reagent. The yield is usually around 80-90%, and the reaction is highly selective, making it a straightforward process.

What industries use Pargyline Hydrochloride (CAS: 306-07-0)?

Pargyline Hydrochloride (CAS: 306-07-0) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of other medicinal compounds. It is also utilized in research laboratories for the development of new drugs and as a reagent in the synthesis of specific molecules. Additionally, it has applications in the chemical industry for the production of certain organic compounds.

What precautions should be taken when handling Pargyline Hydrochloride (CAS: 306-07-0)?

When handling Pargyline Hydrochloride (CAS: 306-07-0), it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. This compound should be stored in a dry, cool place away from direct sunlight. It is flammable and can react with bases, so it should be kept away from strong bases. Handling should be done in a fume hood to minimize exposure to the fumes. In case of a spill, immediately clean up using appropriate procedures and consult the Safety Data Sheet (SDS) for further guidance.