Flunarizine dihydrochloride

Basic Information

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CAS Number

30484-77-6

Molecular Formula

C26H28Cl2F2N2

Molecular Weight

477.43 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

214-217°C

Boiling Point

511.3°C at 760 mmHg

Solubility

chloroform/methanol (9:1): 50 mg/mL, clear, colorless

SMILES

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C1CN(CCN1CC=CC2=CC=CC=C2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl.Cl

InChI

InChI=1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;;

InChIKey

RXKMOPXNWTYEHI-RDRKJGRWSA-N

LogP

6.228800000000007

Topological Polar Surface Area

6.48 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

487

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

EINECS 250-216-6
MFCD00058198
SW196530-3
(E)-1-[Bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)piperazine dihydrochloride
A51066
SR-01000000006-4
s2030
FLUNARIZINE DIHYDROCHLORIDE [MI]
Flunarizine dihydrochloride for system suitability
DTXSID80184554
1-[bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)-piperazine dihydrochloride
1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine dihydrochloride
Flunarizine Dihydrochloride 1.0 mg/ml in Methanol (as free base)
HY-B0358A
NCGC00093920-01
BCP02932
NS00076409
A820398
NCGC00093920-03
FLUNARIZINE DIHYDROCHLORIDE [WHO-DD]
Tox21_500527
Flunarizine hydrochloride,(S)
flunarizine hydrochloride
Flunarizine (dihydrochloride)
30484-77-6
CCG-39000
Flunarizine dihydroch
Flunarizine dihydrochloride, >=98% (TLC)
FLUNARIZINE HYDROCHLORIDE [USAN]
Q27275038
FLUNARIZINE HYDROCHLORIDE [MART.]

MDL Number

MFCD00058198

Customs Code

2933599090

FAQ

What is Flunarizine dihydrochloride (CAS: 30484-77-6)?

Flunarizine dihydrochloride (CAS: 30484-77-6) is a calcium channel blocker used primarily in the treatment of migraines and certain neurological conditions. It is a white to off-white crystalline powder with good solubility in water and is commonly formulated as a tablet or capsule. The compound is known for its ability to reduce vascular spasms and prevent migraine attacks.

What are the main uses of Flunarizine dihydrochloride (CAS: 30484-77-6)?

Flunarizine dihydrochloride (CAS: 30484-77-6) is mainly used in pharmaceutical applications to treat migraines and prevent their recurrence. It is also prescribed for conditions such as trigeminal neuralgia and certain types of vascular headaches. In research settings, it is used to study calcium channel activity and its effects on the nervous system.

Is Flunarizine dihydrochloride (CAS: 30484-77-6) safe?

Flunarizine dihydrochloride (CAS: 30484-77-6) is generally considered safe when used as directed, but it may cause side effects such as drowsiness, weight gain, and gastrointestinal discomfort. It is important to follow prescribed dosages and consult healthcare professionals. Safety standards are in place for its handling and use in both medical and research contexts.

How should Flunarizine dihydrochloride (CAS: 30484-77-6) be stored?

Flunarizine dihydrochloride (CAS: 30484-77-6) should be stored in a cool, dry place away from light. It is typically kept in airtight containers to maintain its stability and prevent moisture absorption. Proper storage ensures the compound remains effective and safe for use over time.