6-(Methylsulfonyl)-1,3-benzothiazole | CAS No. 304660-64-8
6-(Methylsulfonyl)-1,3-benzothiazole
Basic Information
CAS Number
304660-64-8
Molecular Formula
C8H7NO2S2
Molecular Weight
213.28 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- Benzothiazole, 6-(methylsulfonyl)-
- 6-(Methylsulfonyl)benzo[d]thiazole
- 6-METHANESULFONYL-BENZOTHIAZOLE
- 304660-64-8
- SB36483
- 6-METHANESULFONYL-1,3-BENZOTHIAZOLE
- benzothiazole,6-(methylsulfonyl)-
- 6-(Methanesulfonyl)-1,3-benzothiazole
- SCHEMBL12157404
- DTXSID60396875
- 6-methylsulfonyl-1,3-benzothiazole
- Benzothiazole,6-(methylsulfonyl)-
- Benzothiazole, 6-(methylsulfonyl)- (9CI)
MDL Number
MFCD01961205
FAQ
What are the physical and chemical properties of 6-(Methylsulfonyl)-1,3-benzothiazole (CAS: 304660-64-8)?
6-(Methylsulfonyl)-1,3-benzothiazole is a crystalline solid with a molecular weight of approximately 224.26 g/mol. It has a limited water solubility and is soluble in common organic solvents. This compound shows moderate reactivity towards nucleophiles and can participate in electrophilic aromatic substitution reactions. It is stable under normal conditions but should be stored away from strong acids and bases.
How is 6-(Methylsulfonyl)-1,3-benzothiazole (CAS: 304660-64-8) typically synthesized?
6-(Methylsulfonyl)-1,3-benzothiazole can be synthesized through the reaction of methyl methanesulfonate with 1,3-benzothiazole. The reaction is typically carried out in an inert atmosphere using a molecular sieve as a drying agent. The yield is usually around 70-80%, and the reaction is selective for the desired product.
What industries use 6-(Methylsulfonyl)-1,3-benzothiazole (CAS: 304660-64-8)?
6-(Methylsulfonyl)-1,3-benzothiazole is used in the pharmaceutical industry as an intermediate for the synthesis of various drugs, particularly those targeting inflammatory and autoimmune diseases. It is also utilized in the polymer industry for the development of advanced materials. Additionally, it has applications in the field of sensors and semiconductors.
What precautions should be taken when handling 6-(Methylsulfonyl)-1,3-benzothiazole (CAS: 304660-64-8)?
Proper personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat should be worn when handling 6-(Methylsulfonyl)-1,3-benzothiazole. This compound should be stored in a fume hood or a well-ventilated area. In case of spillage, it should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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