5-Bromo-2-chloro-1,3-thiazole

Basic Information

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CAS Number

3034-56-8

Molecular Formula

C3HBrClNS

Molecular Weight

198.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Boiling Point

253.8±32.0 ºC (760 Torr),

Flash Point

107.3±25.1 ºC,

SMILES

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Clc1ncc(Br)s1

InChI

InChI=1S/C3HBrClNS/c4-2-1-6-3(5)7-2/h1H

InChIKey

DKJFZOGJTDCZQU-UHFFFAOYSA-N

LogP

2.559

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

5-Bromo-2-chlorothiazole
5-Bromo-2-chloro-thiazole
5-bromo-2-chloro-1,3-thiazole
2-Chlor-5-bromthiazol
2-Chlor-5-brom-thiazol
2-Chloro-5-bromo-thiazole
2-CHLORO-5-BROMOTHIAZOLE
5-Brom-2-chlor-thiazol
AK-74270
ANW-55085
CTK8B6962
MB14237
QC-6385

MDL Number

MFCD14702782

FAQ

What are the physical and chemical properties of 5-Bromo-2-chloro-1,3-thiazole (CAS: 3034-56-8)?

5-Bromo-2-chloro-1,3-thiazole (CAS: 3034-56-8) is a crystalline compound with a molecular weight of approximately 210.01 g/mol. It has a low water solubility and is sparingly soluble in organic solvents like ethanol and acetone. The compound exhibits moderate reactivity, particularly towards nucleophiles and electrophiles. It is commonly used in organic synthesis and pharmaceuticals.

How is 5-Bromo-2-chloro-1,3-thiazole (CAS: 3034-56-8) typically synthesized?

5-Bromo-2-chloro-1,3-thiazole (CAS: 3034-56-8) is often synthesized via a multi-step process involving bromination and chlorination reactions of thiazole. Commonly, thiazole is treated with bromine and chlorine in the presence of a suitable solvent and catalyst to achieve the desired product with high yield and selectivity.

What industries use 5-Bromo-2-chloro-1,3-thiazole (CAS: 3034-56-8)?

5-Bromo-2-chloro-1,3-thiazole (CAS: 3034-56-8) is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It also has potential applications in the polymer industry for the development of novel materials. Additionally, this compound can be used in the production of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 5-Bromo-2-chloro-1,3-thiazole (CAS: 3034-56-8)?

When handling 5-Bromo-2-chloro-1,3-thiazole (CAS: 3034-56-8), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up according to the Material Safety Data Sheet (MSDS) guidelines. Always consult the SDS for detailed safety information.