1-[(4-Chlorophenyl)(phenyl)methyl]piperazine

Basic Information

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CAS Number

303-26-4

Molecular Formula

C17H19ClN2

Molecular Weight

286.81 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

65-70 °C

Boiling Point

178-180 °C/0.5 mmHg

Refractive Index

1.5749 (estimate)

SMILES

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C1CN(CCN1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl

InChI

InChI=1S/C17H19ClN2/c18-16-8-6-15(7-9-16)17(14-4-2-1-3-5-14)20-12-10-19-11-13-20/h1-9,17,19H,10-13H2

InChIKey

UZKBSZSTDQSMDR-UHFFFAOYSA-N

LogP

3.334600000000002

Topological Polar Surface Area

15.27 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

277

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

CS-W001978
SB47944
T875VN0D6E
FT-0629215
Piperazine, 1-(alpha-(4-chlorophenyl)benzyl)-
Piperazine, 1-(p-chloro-.alpha.-phenylbenzyl)-
(-)-1-[(4-chloro phenyl)phenylmethyl]piperazine
C1611
FT-0604324
(-)-1-[(4-Chloro-phenyl)-phenyl-methyl]-piperazine
1-[(4-chlorophenyl)-phenylmethyl]-piperazine
AC-3019
Levocetirizine Impurity 2
EU-0099994
1-[(4-Chloro-phenyl)-phenyl-methyl]-piperazine
CHEMBL81324
HMS2464F07
Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-
4-CHLOROBENZHYDRYLPIPERAZINE
NSC 86164
(S)-Nor-CCZ
Piperazine, 1-((4-chlorophenyl)phenylmethyl)-
HYDROXYZINE HYDROCHLORIDE IMPURITY A [EP IMPURITY]
Cetirizine Impurity A
SY003580
1-(4-Chlorobenzhydryl)piperazine
GTPL9162
EN300-18220
Q-200042
NS00000628
CETIRIZINE DIHYDROCHLORIDE IMPURITY A [EP IMPURITY]

MDL Number

MFCD00005965

Customs Code

2933599090

FAQ

What is 1-[(4-Chlorophenyl)(phenyl)methyl]piperazine ( CAS: 303-26-4 )?

1-[(4-Chlorophenyl)(phenyl)methyl]piperazine (CAS: 303-26-4) is a piperazine derivative with the molecular formula C15H18ClN2. It is a white to off-white solid with moderate solubility in organic solvents. The compound features a bridging structure connecting two phenyl groups (one substituted with chlorine) to a piperazine ring, making it valuable in organic synthesis.

What are the main uses of 1-[(4-Chlorophenyl)(phenyl)methyl]piperazine ( CAS: 303-26-4 )?

1-[(4-Chlorophenyl)(phenyl)methyl]piperazine (CAS: 303-26-4) is primarily used in pharmaceutical research as an intermediate for drug development. It may also serve as a building block in agrochemicals and materials science. Its unique structure makes it applicable in creating compounds with biological activity, though specific commercial uses are limited in public databases.

Is 1-[(4-Chlorophenyl)(phenyl)methyl]piperazine ( CAS: 303-26-4 ) safe?

1-[(4-Chlorophenyl)(phenyl)methyl]piperazine (CAS: 303-26-4) requires careful handling due to potential toxicity. It may cause skin irritation or respiratory issues upon exposure. Safety protocols include wearing protective gloves, goggles, and a lab coat, and working in a well-ventilated area. Always consult a safety data sheet (SDS) for detailed guidelines.

How should 1-[(4-Chlorophenyl)(phenyl)methyl]piperazine ( CAS: 303-26-4 ) be stored?

1-[(4-Chlorophenyl)(phenyl)methyl]piperazine (CAS: 303-26-4) should be stored in a cool, dry place, away from light and moisture. Keep in a sealed, airtight container made of inert material to prevent degradation. Stability is maintained under normal conditions, but avoid exposure to heat and air to ensure longevity.