2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide

Basic Information

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CAS Number

302964-24-5

Molecular Formula

C11H10ClN3OS

Molecular Weight

267.74 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Powder

Melting Point

208.0 to 212.0 deg-C

Boiling Point

362°C at 760 mmHg

SMILES

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CC1=CC=CC(Cl)=C1NC(=O)C1=CN=C(N)S1

InChI

InChI=1S/C11H10ClN3OS/c1-6-3-2-4-7(12)9(6)15-10(16)8-5-14-11(13)17-8/h2-5H,1H3,(H2,13,14)(H,15,16)

InChIKey

VVOXTERFTAJMAA-UHFFFAOYSA-N

LogP

2.93942

Topological Polar Surface Area

68.01 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

292

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide
Dasatinib IMpurity 2
2-AMino-N-(2-chloro-6-Methylphenyl)thiazole-5-carboxiMide)
2-Amino-5-[(2-chloro-6-methylphenyl)carbamoyl]-1,3-thiazole, 2-Amino-5-[(6-chloro-o-tolyl)carbamoyl]-1,3-thiazole
2-AMino-N-(2-chloro-6-Methylphenyl)-5-thiazolecarboxaMide
5-ThiazolecarboxaMide,2-aMino-N-(2-chloro-6-Methylphenyl)
Dasatinib Int N-2
2-amino-N-(2-chloro-6-methylphenyl)-1,3-thiazole-5-carboxamide
2-amino-N-(2-cliloro-6-metliylplienyl)thiazole-5-carboxamide
2-aminothiazole-5-carboxylic acid (2-chloro-6-methylphenyl)amide
N-(2-chloro-6-methylphenyl)-2-amino-5-thiazolecarboxamide
2-amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide

MDL Number

MFCD10000630

Customs Code

2934100090

FAQ

What is 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide (CAS: 302964-24-5)?

2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide (CAS: 302964-24-5) is a thiazole derivative with the chemical formula C12H11ClN2O2S. It is a white to pale yellow solid with moderate solubility in polar solvents. The compound exhibits functional group characteristics of an amide and a thiazole ring, making it relevant in organic synthesis and pharmaceutical research.

What are the main uses of 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide (CAS: 302964-24-5)?

2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide (CAS: 302964-24-5) is primarily used in pharmaceutical development as an intermediate in the synthesis of various drugs. It also finds applications in chemical research for its reactivity and structural versatility, and may be used in industrial processes for the production of specialized chemicals and materials.

Is 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide (CAS: 302964-24-5) safe?

2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide (CAS: 302964-24-5) is generally considered safe when handled properly. However, it may cause mild irritation to the skin and eyes. Precautions include using appropriate personal protective equipment (PPE) and following standard laboratory safety protocols. Safety data sheets (SDS) should be consulted for detailed handling and exposure guidelines.

How should 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide (CAS: 302964-24-5) be stored?

2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide (CAS: 302964-24-5) should be stored in a cool, dry, and dark place, away from moisture and incompatible substances. It is best kept in a sealed container at a temperature below 25°C and in a humidity-controlled environment to maintain stability and prevent degradation.