piperazine-2-carboxylic acid dihydrochloride

Basic Information

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CAS Number

3022-15-9

Molecular Formula

C5H12Cl2N2O2

Molecular Weight

203.07 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

265 °C (dec.)

Boiling Point

313.6 °C at 760 mmHg

Density

1.174

Flash Point

143.5℃

Refractive Index

1.476

SMILES

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C1CNC(CN1)C(=O)O.Cl.Cl

InChI

InChI=1S/C5H10N2O2.2ClH/c8-5(9)4-3-6-1-2-7-4;;/h4,6-7H,1-3H2,(H,8,9);2*1H

InChIKey

WNSDZBQLMGKPQS-UHFFFAOYSA-N

LogP

-0.5240000000000002

Topological Polar Surface Area

61.36 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

116

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

MFCD03840829
AM20090413
SY004769
piperazine-2-carboxylic acid 2hcl
Piperazine-2-carboxylic acid dihydrochloride
2-Piperazinecarboxylic acid, dihydrochloride
TS-00347
W-205424
PB21831
1,2,5-Thiadiazoles
FT-0643198
piperazine-2-carboxylic acid dihydrochloride;PIPERAZINE-2-CARBOXYLIC ACID 2HCL
SY017866
EN300-67574
F8889-2135
FT-0630196
Z1273089259
133525-05-0
J-502272
(R)-(+)-2-Piperazinecarboxylic acid dihydrochloride
Piperazine-1,4-diium-2-carboxylic acid;dichloride
Vildagliptin-boronic?acid
WNSDZBQLMGKPQS-UHFFFAOYSA-N
3022-15-9
(+/-)-Piperazine-2-carboxylic acid dihydrochloride
DTXSID00928174
piperazine-2-carboxylic acid;dihydrochloride
PB24733
BCP33985
(+/-)-2-piperazinecarboxylic acid dihydrochloride
2-piperazine-carboxylic acid dihydrochloride

MDL Number

MFCD00044803

FAQ

What are the physical and chemical properties of piperazine-2-carboxylic acid dihydrochloride (CAS: 3022-15-9)?

Piperazine-2-carboxylic acid dihydrochloride (CAS: 3022-15-9) is a crystalline solid with a molecular weight of approximately 240.86 g/mol. It has a high water solubility, making it soluble in water up to 100 mg/mL. Chemically, it is highly reactive, particularly in acidic conditions, and can form stable complexes with metal ions.

How is piperazine-2-carboxylic acid dihydrochloride (CAS: 3022-15-9) typically synthesized?

Piperazine-2-carboxylic acid dihydrochloride is typically synthesized by reacting piperazine-2-carboxylic acid with hydrochloric acid in an aqueous solution. The reaction is mild, usually conducted at room temperature, and yields a dihydrochloride salt with high selectivity and good yield.

What industries use piperazine-2-carboxylic acid dihydrochloride (CAS: 3022-15-9)?

Piperazine-2-carboxylic acid dihydrochloride (CAS: 3022-15-9) finds applications in the pharmaceutical industry for the synthesis of certain drugs, in the polymer industry for the modification of polymer properties, and in the sensor industry for the development of gas-sensing devices. It is also used in the semiconductor industry for the production of organic semiconductors.

What precautions should be taken when handling piperazine-2-carboxylic acid dihydrochloride (CAS: 3022-15-9)?

When handling piperazine-2-carboxylic acid dihydrochloride (CAS: 3022-15-9), it is important to wear appropriate personal protective equipment (PPE) such as gloves and goggles. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation of dust. Spills should be cleaned up using appropriate methods, and safety data sheets (SDS) should be consulted for detailed handling and disposal procedures.