Retinoic acid

Basic Information

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CAS Number

302-79-4

Molecular Formula

C20H28O2

Molecular Weight

300.44 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Yellow powder

Melting Point

180-181 °C

Boiling Point

462.8°C at 760 mmHg

Flash Point

350.6±11.0 °C

Refractive Index

1.4800 (estimate)

Vapor Pressure

0.0±2.5 mmHg at 25°C

SMILES

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CC(=CC=CC(=CC(=O)O)C)/C=C/C1=C(C)CCCC1(C)C

InChI

InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6?,12-11+,15-8?,16-14?

InChIKey

SHGAZHPCJJPHSC-CWOWKJJZSA-N

LogP

5.602600000000005

Topological Polar Surface Area

37.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

567

Safety Information

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GHS Hazard Pictograms

H302

H411

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H411 Toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 6.1(b) Class 6.1(b)

Stability

Store Dry in Freezer at -20°C for up to 1 year; in Solution at -20°C for up to 3 Months.

Sensitiveness

Light Sensitive

Toxicity

LD50 (10 day) in mice, rats (mg/kg): 790, 790 i.p.; 2200, 2000 orally (Kamm)

Synonyms & References

English

(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
13-CIS-RETINOIC ACID
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2E,4E,6E,8E-NONATETRAENOIC ACID
3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2Z,4E,6E,8E-NONATETRANENOIC ACID
9-TRANS-RETINOIC ACID
9-TRANS-TRETINOIN
AKOS 92103
ALL-TRANS-RETINOIC ACID
ALL-TRANS-RETINOIE ACID
ALL-TRANS-VITAMIN A ACID
ISOTRETINOIN
(L)-ISOTRETINOIN
RETINOIC ACID
RETINOIC ACID, 13-CIS-
RETINOIC ACID, ALL TRANS
RETINOIC ACID ALL TRANS ISOMER
TRANS-RETINOIC ACID
TRANS VITAMIN A ACID
TRETINOIN
vitamin A acid
(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
all-trans-Retinoic A
Tretinoin (Retinoic acid)
Tretinoin ,(All-Trans Retinoic Acid)
ATRA
(all-e)
[3H]-Retinoic Acid
aberel
aknoten
all-trans retinoic acid

MDL Number

MFCD00001551

Customs Code

2916209090

FAQ

What is [compound name] (CAS: 302-79-4)?

Retinoic acid, with the CAS number 302-79-4, is a derivative of vitamin A. Its chemical formula is C20H28O2. It is a colorless to pale yellow crystalline solid with a slightly fishy odor. Retinoic acid is known for its role in cellular growth and differentiation, and it is a key component in the regulation of skin health and development.

What are the main uses of [compound name] (CAS: 302-79-4)?

Retinoic acid is primarily used in dermatology for treating acne and promoting skin renewal. It is also employed in pharmaceuticals for its role in regulating cell growth, and in research for studying biological processes. Additionally, it is used in the production of certain vitamins and as a precursor in the synthesis of other retinoids.

Is [compound name] (CAS: 302-79-4) safe?

Retinoic acid is generally considered safe when used as directed in topical treatments or under medical supervision. However, it can be toxic if ingested in large amounts, leading to symptoms like dizziness, nausea, and liver damage. Proper handling and adherence to safety guidelines are essential to avoid adverse effects.

How should [compound name] (CAS: 302-79-4) be stored?

Retinoic acid should be stored in a cool, dry place away from light and moisture. It is typically kept in sealed containers to maintain its stability and prevent degradation. Handling should be done with care to avoid exposure to air and heat, which can affect its potency and safety.