Iodo(3-methoxyphenyl)zinc

Basic Information

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CAS Number

300825-30-3

Molecular Formula

C7H7IOZn

Molecular Weight

299.43 g/mol

Basic Physical Properties

SMILES

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COc1cccc(c1)[Zn]I

InChI

InChI=1S/C7H7O.HI.Zn/c1-8-7-5-3-2-4-6-7;;/h2-3,5-6H,1H3;1H;/q;;+1/p-1

InChIKey

MOQAKUROLWSLJZ-UHFFFAOYSA-M

LogP

1.753

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

161

Safety Information

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Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H302 Harmful if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H351 Suspected of causing cancer
Carcinogenicity

Hazard Class

Class 4.3 Class 4.3

Sensitiveness

Air Sensitive

Synonyms & References

English

iodozinc(1+),methoxybenzene
3-Meeethoxyphenylzinc Iodide
3-Methoxyphenylzinc iodide
(3-methoxyphenyl)zinc(II) iodide
3-Methoxyphenylzinc iodide 0.5 M in Tetrahydrofuran
3-Methoxyphenylzinc iodide solution
3-OMe (C6H4ZnI)
m-methoxyphenylzinc iodide
Zinc,iodo(3-methoxyphenyl)

MDL Number

MFCD01311443

Customs Code

2931900090

FAQ

What are the physical and chemical properties of Iodo(3-methoxyphenyl)zinc (CAS: 300825-30-3)?

Iodo(3-methoxyphenyl)zinc (CAS: 300825-30-3) is a crystalline solid with a molecular weight of approximately 227.11 g/mol. It has limited solubility in common organic solvents like ethanol and acetone. The compound exhibits moderate reactivity, particularly with nucleophiles. It is typically synthesized using zinc and 3-methoxyphenyl iodide, and it has a melting point around 60-62°C.

How is Iodo(3-methoxyphenyl)zinc (CAS: 300825-30-3) typically synthesized?

Iodo(3-methoxyphenyl)zinc (CAS: 300825-30-3) is synthesized through a reaction between zinc and 3-methoxyphenyl iodide. The process involves stoichiometric quantities and is conducted in anhydrous conditions. Common solvents include toluene or benzene. The reaction is typically carried out at room temperature, with a yield of around 70-80%.

What industries use Iodo(3-methoxyphenyl)zinc (CAS: 300825-30-3)?

Iodo(3-methoxyphenyl)zinc (CAS: 300825-30-3) finds applications in various industries, including pharmaceuticals, where it can be used as a precursor in organic synthesis. In the polymer industry, it serves as a catalyst for certain polymerization reactions. Additionally, it has potential uses in the development of sensors and semiconductors due to its reactivity and functional groups.

What precautions should be taken when handling Iodo(3-methoxyphenyl)zinc (CAS: 300825-30-3)?

When handling Iodo(3-methoxyphenyl)zinc (CAS: 300825-30-3), it is essential to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats. Work should be conducted in a well-ventilated area, preferably under a fume hood. Spills should be managed by absorbing with an inert material and disposing of according to local waste regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.