1-[(R)-(4-Chlorophenyl)(phenyl)methyl]piperazine

Basic Information

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CAS Number

300543-56-0

Molecular Formula

C17H19ClN2

Molecular Weight

286.81 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

409.1°C at 760 mmHg

Water Solubility

Soluble in chloroform, methanol, and dichloromethane. Slightly soluble in water.

SMILES

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C1CN(CCN1)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl

InChI

InChI=1S/C17H19ClN2/c18-16-8-6-15(7-9-16)17(14-4-2-1-3-5-14)20-12-10-19-11-13-20/h1-9,17,19H,10-13H2/t17-/m1/s1

InChIKey

UZKBSZSTDQSMDR-QGZVFWFLSA-N

LogP

3.334600000000002

Topological Polar Surface Area

15.27 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

277

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

C17H19ClN2
CHEMBL3771137
Piperazine, 1-[(R)-(4-chlorophenyl)phenylmethyl]-
UZKBSZSTDQSMDR-QGZVFWFLSA-N
A5547
MFCD11519277
(R)-1-((4-Chlorophenyl)(phenyl)methyl)piperazine (Cetirizine Impurity)
AKOS015900420
1-[(R)-(4-chlorophenyl)-phenylmethyl]piperazine
DS-16464
(R)-1-(p-Chlorobenzhydryl)piperazine
Piperazine, 1-((R)-(4-chlorophenyl)phenylmethyl)-
1-[(r)-(4-chlorophenyl)(phenyl)methyl]piperazine
(R)-1-((4-CHLOROPHENYL)PHENYLMETHYL)PIPERAZINE
300543-56-0
(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
(-)-1-((4-Chlorophenyl)phenylmethyl)piperazine
CS-0156606
(R)-N-(4-Chlorobenzyl hydryl) piperazine
(-)-norchlorcyclizine
Q27269970
AKOS016016508
CS-0200360
1-[(R)-(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE,
AC-26786
(-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
J-017749
CHLOROBENZHYDRYL PIPERAZINE [USP-RS]
[(1R)(4-chlorophenyl)phenylmethyl]piperazine
(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine; Piperazine, 1-[(R)-(4-chlorophenyl)phenylmethyl]-; (-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine; (R)-1-(p-Chlorobenzhydryl)piperazine; 1-[(R)-alpha-(4-Chlorophenylbenzyl]piperazine; N-[(R)-alpha-(4-Chlorophenylbenzyl]piperazine
SCHEMBL588655

MDL Number

MFCD11519277

Customs Code

2933599090

FAQ

What regulatory guidelines apply to 1-[(R)-(4-Chlorophenyl)(phenyl)methyl]piperazine (CAS: 300543-56-0)?

1-[(R)-(4-Chlorophenyl)(phenyl)methyl]piperazine (CAS: 300543-56-0) is subject to the GHS classification, which includes its hazard communication and classification as an irritant. In the EU, it falls under REACH regulations, which require registration and notification to authorities. For FDA/EPA in the USA, it must comply with the Toxic Substances Control Act (TSCA) and the regulations regarding the handling of hazardous substances.

Are there alternatives to 1-[(R)-(4-Chlorophenyl)(phenyl)methyl]piperazine (CAS: 300543-56-0) in synthesis?

There are several alternatives to 1-[(R)-(4-Chlorophenyl)(phenyl)methyl]piperazine in synthesis, such as 1-[(S)-(4-Chlorophenyl)(phenyl)methyl]piperazine, other piperazine derivatives, or other substituted piperazines. These alternatives can offer similar functionality with varying properties and synthesis complexities.

What is the market or research trend for 1-[(R)-(4-Chlorophenyl)(phenyl)methyl]piperazine (CAS: 300543-56-0)?

The market for 1-[(R)-(4-Chlorophenyl)(phenyl)methyl]piperazine (CAS: 300543-56-0) is growing due to its use in research applications, particularly in drug discovery and development. Recent research trends show an increasing interest in its potential as a pharmacological agent. Market demand is also influenced by regulatory approvals and advancements in chemical synthesis techniques.

How should waste containing 1-[(R)-(4-Chlorophenyl)(phenyl)methyl]piperazine (CAS: 300543-56-0) be handled?

Waste containing 1-[(R)-(4-Chlorophenyl)(phenyl)methyl]piperazine (CAS: 300543-56-0) should be collected in appropriate containers and stored in a secure location. Proper incineration or professional waste disposal services should be used to ensure safe disposal. Environmental precautions include the use of protective gear and adherence to local hazardous waste management regulations to prevent contamination of soil and water sources.