9-(5-O-Phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine

Basic Information

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CAS Number

29984-33-6

Molecular Formula

C10H14N5O7P

Molecular Weight

347.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Melting Point

213 ºC

Water Solubility

Soluble in water at 4mg/ml

SMILES

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C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O)N

InChI

InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7+,10-/m1/s1

InChIKey

UDMBCSSLTHHNCD-UHTZMRCNSA-N

LogP

-1.8630000000000002

Topological Polar Surface Area

186.07 Å²

Hydrogen Bond Donor/Acceptor

6 / 12

Complexity

481

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H360 May damage fertility or the unborn child
Reproductive toxicity

Hazard Class

Class 6.1(a) Class 6.1(a)

Synonyms & References

English

9H-Purin-6-amine, 9-(5-O-phosphono-b-D-arabinofuranosyl)-
EINECS 249-990-8
NS00084024
araAMP
Vidarabine phosphate [USAN]
A820136
A5O
Adenine arabinonucleoside 5'-phosphate
9H-Purin-6-amine, 9-(5-O-phosphono-b-D-arabinofuranosyl)-;
HG1004
9-(b-D-Arabinofuranosyl)adenine 5'-monophosphate
[(2R,3S,4S,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
AS-70487
5'-Arabinosyladenine monophosphate
Vidarabine monophosphate
D-Arabinosyladenine 5'-monophosphate
Vidarabine-5'-monophosphate
SCHEMBL144996
CL-808
106XV160TZ
UNII-106XV160TZ
Vidarabine phosphate (USAN)
Adenine, 9-beta-D-arabinofuranosyl-, 5'-(dihydrogen phosphate)
BCP10479
9-(.beta.-D-Arabinofuranosyl)adenine-5'-phosphate
Adenine, 9beta-D-arabinofuranosyl-, 5'-(dihydrogen phosphate)
VIDARABINE PHOSPHATE [WHO-DD]
D06299
9-(b-D-Arabinofuranosyl)adenine5'-monophosphate
NSC127223
Adenosine arabinoside-5'-phosphate

MDL Number

MFCD00069723

FAQ

What regulatory guidelines apply to 9-(5-O-Phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine (CAS: 29984-33-6)?

Regulatory guidelines for 9-(5-O-Phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine (CAS: 29984-33-6) include GHS classification for hazardous materials, REACH regulations in the European Union, and FDA and EPA requirements for pharmaceutical and environmental safety. These guidelines ensure the safe handling, storage, and disposal of the compound.

Are there alternatives to 9-(5-O-Phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine (CAS: 29984-33-6) in synthesis?

In the synthesis of nucleosides, there are alternatives to 9-(5-O-Phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine (CAS: 29984-33-6), such as using other sugar analogs like 2-deoxy or 2-fluoro sugar derivatives, or employing different phosphoramidite reagents. These alternatives offer varying levels of reactivity and selectivity in the synthesis process.

What is the market or research trend for 9-(5-O-Phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine (CAS: 29984-33-6)?

The research trend for 9-(5-O-Phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine (CAS: 29984-33-6) focuses on its potential as a nucleoside analog for therapeutic applications, particularly in antiviral treatments. Market trends indicate increasing interest in nucleoside-based drugs, driven by advancements in molecular biology and the need for new antiviral therapies.

How should waste containing 9-(5-O-Phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine (CAS: 29984-33-6) be handled?

Waste containing 9-(5-O-Phosphono-beta-D-arabinofuranosyl)-9H-purin-6-amine (CAS: 29984-33-6) should be collected in appropriate containers and stored under controlled conditions. It should then be incinerated or disposed of through professional waste disposal services that meet regulatory standards. Environmental precautions include thorough neutralization and detoxification before disposal to prevent contamination.