S-Adenosyl-L-Methionine

Basic Information

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CAS Number

29908-03-0

Molecular Formula

C15H22N6O5S

Molecular Weight

398.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O

InChI

InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/t7-,8+,10+,11+,14+,27?/m0/s1

InChIKey

MEFKEPWMEQBLKI-AIRLBKTGSA-N

LogP

-0.26280

Complexity

527

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

[14COOH]AdoMet
(2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(methyl)sulfanylium)butanoate
S-ADENOSYLMETHIONINE [VANDF]
ADEMETIONINE DISULFATE DITOSYLATE
CCRIS 7130
ADEMETIONINE [WHO-DD]
UNII-7LP2MPO46S
(2S)-2-Amino-4-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonio)butanoate
S-adenosyl-L-methionine
Adenosine, 5'-((R)-((3S)-3-amino-3-carboxypropyl)methylsulfonio)-5'-deoxy-, inner salt
Adenosine, 5'-((3-amino-3-carboxypropyl)methylsulfonio)-5'-deoxy-, inner salt, (3S)-
Adenosine, 5'-(((3S)-3-amino-3-carboxypropyl)methylsulfonio)-5'-deoxy-, inner salt
S-Adenosyl-L-Methtonine
29908-03-0
Adenosine, 5'-((L-3-amino-3-carboxypropyl)methylsulfonio)-5'-deoxy-, hydroxide, inner salt
SAMe
Ademetionine, (R)-
adenosylmethionine
Donamet
Transmetil
Adenosine, 5'-[(L-3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxy-, hydroxide, inner salt (8CI)
Active methionine
AKOS040750137
AC-19717
S-adenosylmethionine
[(3S)-3-amino-3-carboxylatopropyl](5'-deoxyadenosin-5'-yl)(methyl)sulfonioacetate
Methionine, S-adenosyl-
CHEMBL1235831
S-(5'-DESOXYADENOSIN-5'-YL)-L-METHIONINE
S-Adenosyl-L-methionine;S-Adenosyl methionine;SAMe;AdoMet
S. Amet

MDL Number

MFCD00871208

Customs Code

2934999090

FAQ

What is S-Adenosyl-L-Methionine (CAS: 29908-03-0)?

S-Adenosyl-L-Methionine (SAM), with the CAS number 29908-03-0, is a vital coenzyme involved in methylation reactions. Its chemical formula is C10H17N6O4S, and it functions as a methyl donor in biological systems. SAM plays a key role in DNA synthesis, neurotransmitter production, and detoxification processes. It is naturally present in all living cells and is essential for maintaining cellular function and metabolic balance.

What are the main uses of S-Adenosyl-L-Methionine (CAS: 29908-03-0)?

S-Adenosyl-L-Methionine (CAS: 29908-03-0) is widely used in pharmaceuticals for treating depression, fibromyalgia, and chemotherapy-induced mucositis. In the food industry, it is a natural component of plants and animals, contributing to flavor and aroma. Research applications include epigenetics and drug development, while industrial uses involve chemical synthesis and as a methylating agent. Its versatility makes it a critical compound in multiple fields.

Is S-Adenosyl-L-Methionine (CAS: 29908-03-0) safe?

S-Adenosyl-L-Methionine (CAS: 29908-03-0) is generally safe when used as directed, with minimal toxicity in recommended doses. However, high concentrations may cause gastrointestinal discomfort or allergic reactions. Proper handling, such as wearing gloves and ensuring ventilation, is advised. Safety standards emphasize adherence to regulatory guidelines, making it suitable for therapeutic and industrial applications with appropriate precautions.

How should S-Adenosyl-L-Methionine (CAS: 29908-03-0) be stored?

S-Adenosyl-L-Methionine (CAS: 29908-03-0) should be stored in a cool, dry place away from moisture and light. Maintain storage conditions below 25°C and ensure humidity levels are low. Use airtight, moisture-proof containers to preserve stability. Avoid exposure to incompatible substances and store in a well-ventilated area to maintain quality and safety.