2-[4-(Trifluoromethyl)phenyl]pyrrolidine

Basic Information

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CAS Number

298690-84-3

Molecular Formula

C11H12F3N

Molecular Weight

215.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

254.1°Cat760mmHg

Density

1.179

Flash Point

107.5°C

Refractive Index

1.473

SMILES

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C1CC(NC1)C2=CC=C(C=C2)C(F)(F)F

InChI

InChI=1S/C11H12F3N/c12-11(13,14)9-5-3-8(4-6-9)10-2-1-7-15-10/h3-6,10,15H,1-2,7H2

InChIKey

GSOGADJIIMVREB-UHFFFAOYSA-N

LogP

3.129900000000001

Topological Polar Surface Area

12.03 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

206

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2-(4-(trifluoromethyl)phenyl)pyrrolidine
2-(4-trifluoromethylphenyl)pyrrolidine
(RS)-2-(4-trifluoromethyl-phenyl)-pyrrolidine
DTXSID70395238
Pyrrolidine, 2-[4-(trifluoromethyl)phenyl]-
AKOS000174039
298690-84-3
AKOS016352876
CS-0155426
2-(4-Trifluoromethylphenyl)-pyrrolidine
2-[4-(trifluoromethyl)phenyl]pyrrolidine
2-(4-trifluoromethylphenyl)pyrrolidine, AldrichCPR
AC-5476
AR1043
SB49732
FT-0644365
A26420
MFCD01631837
SCHEMBL3597818
2-(4-Trifluoromethyl-phenyl)pyrrolidine
PS-6898
EN300-1124798
2-(4-Trifluoromethylphenyl)pyrrolidine
2-[4-(Trifluoromethyl)phenyl]pyrrolidine
AC1MV2GA
AC1Q4J2T
ACMC-209hbi
SureCN3597818

MDL Number

MFCD01631837

Customs Code

2933990090

FAQ

What regulatory guidelines apply to 2-[4-(Trifluoromethyl)phenyl]pyrrolidine (CAS: 298690-84-3)?

2-[4-(Trifluoromethyl)phenyl]pyrrolidine (CAS: 298690-84-3) falls under various regulatory guidelines such as the Globally Harmonized System (GHS) for classification and labeling of chemicals, REACH regulations in Europe, and FDA/EPA environmental and safety standards. Specific handling and storage guidelines are outlined in these documents to ensure safe and compliant management of the compound.

Are there alternatives to 2-[4-(Trifluoromethyl)phenyl]pyrrolidine (CAS: 298690-84-3) in synthesis?

Alternatives to 2-[4-(Trifluoromethyl)phenyl]pyrrolidine (CAS: 298690-84-3) include other pyrrolidine derivatives such as 2-pyrrolidinone and 2-methylpyrrolidine. Trifluoromethyl-substituted isomers and analogs like 3-(trifluoromethyl)pyrrolidine can also be considered depending on the specific requirements of the synthesis. These alternatives offer similar functionalities but with varying properties and reactivities.

What is the market or research trend for 2-[4-(Trifluoromethyl)phenyl]pyrrolidine (CAS: 298690-84-3)?

The market for 2-[4-(Trifluoromethyl)phenyl]pyrrolidine (CAS: 298690-84-3) is growing due to its applications in pharmaceuticals and as a precursor in organic synthesis. Research trends focus on its use in developing new drug molecules and materials. Recent studies are also exploring its potential in biocatalysis and as a chiral auxiliary. Market demand is expected to increase with ongoing biotech and pharmaceutical innovations.

How should waste containing 2-[4-(Trifluoromethyl)phenyl]pyrrolidine (CAS: 298690-84-3) be handled?

Waste containing 2-[4-(Trifluoromethyl)phenyl]pyrrolidine (CAS: 298690-84-3) should be collected in appropriate containers and stored in a well-ventilated area. Incineration is a common disposal method, but professional waste disposal companies are recommended to ensure compliance with local regulations. Environmental precautions include minimizing exposure to air, water, and soil, and adhering to safe handling and transport guidelines.