1-(Diphenylmethyl)-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine

Basic Information

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CAS Number

298-57-7

Molecular Formula

C26H28N2

Molecular Weight

368.52 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

117.0 to 121.0 deg-C

Boiling Point

505.8°C at 760 mmHg

Solubility

Soluble in chloroform at 50mg/ml

Refractive Index

1.7620 (estimate)

SMILES

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C1CN(CCN1CC=CC2=CC=CC=C2)C(C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChI=1S/C26H28N2/c1-4-11-23(12-5-1)13-10-18-27-19-21-28(22-20-27)26(24-14-6-2-7-15-24)25-16-8-3-9-17-25/h1-17,26H,18-22H2/b13-10+

InChIKey

DERZBLKQOCDDDZ-JLHYYAGUSA-N

LogP

5.1070000000000055

Topological Polar Surface Area

6.48 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

429

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 9 Class 9

Synonyms & References

English

NCGC00018187-04
HMS3260P10
Apotomin
Piperazine, (E)-
N90
MLS002207295
Piperazine, 1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-
EINECS 206-064-8
Cinnarizinum
Piperazine, 1-cinnamyl-4-(diphenylmethyl)-
Corathiem
Sepan
HMS3885F20
C 5270
NCGC00018187-14
Q775073
1-[di(phenyl)methyl]-4-(3-phenylprop-2-enyl)piperazine
Toliman
NSC290687
Senoger
CHEMBL43064
HMS2234B20
NCGC00018187-09
Cinnacet
CINNARIZINE [MART.]
NCGC00015246-02
component of Emesazine (Salt/Mix)
BRD-K74927006-001-01-2
NCGC00021488-04
R 1575
NCGC00018187-07

MDL Number

MFCD00056037

Customs Code

2933599090

FAQ

What is 1-(Diphenylmethyl)-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine (CAS: 298-57-7)?

1-(Diphenylmethyl)-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine (CAS: 298-57-7) is a piperazine derivative with a complex structure containing diphenylmethyl and (2E)-3-phenyl-2-propenyl groups. It is a white to off-white solid with low solubility in water and is commonly used in chemical research for its pharmacological and biological properties.

What are the main uses of 1-(Diphenylmethyl)-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine (CAS: 298-57-7)?

This compound is primarily used in pharmaceutical research as a potential drug candidate, particularly in the development of antipsychotic and antidepressant medications. It also finds applications in organic synthesis and as a compound of interest in medicinal chemistry due to its structural versatility and biological activity.

Is 1-(Diphenylmethyl)-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine (CAS: 298-57-7) safe?

1-(Diphenylmethyl)-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine (CAS: 298-57-7) is considered safe in controlled laboratory settings when handled properly. However, it may have potential toxicity if ingested or inhaled, so protective measures such as gloves, goggles, and a fume hood are recommended. Safety data is limited, and further research is needed for comprehensive evaluation.

How should 1-(Diphenylmethyl)-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine (CAS: 298-57-7) be stored?

1-(Diphenylmethyl)-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine (CAS: 298-57-7) should be stored in a cool, dry, and dark place, away from moisture and incompatible substances. It is best kept in a sealed container at a temperature below 25°C to maintain stability and prevent degradation.