Methyl 4-methoxy-2-pyridinecarboxylate

Basic Information

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CAS Number

29681-43-4

Molecular Formula

C8H9NO3

Molecular Weight

167.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

No data available

Melting Point

50.0 to 54.0 deg-C

Boiling Point

280.4℃ at 760 mmHg

Density

1.156

Flash Point

123.4±21.8 °C

Refractive Index

1.503

SMILES

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COC1=CC(=NC=C1)C(=O)OC

InChI

InChI=1S/C8H9NO3/c1-11-6-3-4-9-7(5-6)8(10)12-2/h3-5H,1-2H3

InChIKey

OJDKENGKKYVJLY-UHFFFAOYSA-N

LogP

0.8767999999999999

Topological Polar Surface Area

48.42 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

160

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

A5510
METHYL 4-METHOXY-2-PYRIDINECARBOXYLATE
methyl 4-methoxypicolinate
BB 0257355
MFCD00956223
FT-0638875
4-Methoxy-pyridine-2-carboxylic acid methyl ester, AldrichCPR
4-Methoxy-pyridine-2-carboxylic acid methyl ester
M2508
AKOS005264966
CL0186
OJDKENGKKYVJLY-UHFFFAOYSA-N
AC-23219
4-Methoxypicolinic Acid Methyl Ester
BCP09360
AM803653
EN300-119830
AB07787
4-methoxy-pyridine-2-carboxylicacidmethylester
PS-3444
SY007556
SCHEMBL1703544
J-522369
Methyl4-methoxypyridine-2-carboxylate
Methyl 4-methoxypyridine-2-carboxylate
DTXSID50364008
4-Methoxy-pyridine-2-carboxylic acid metyl ester
29681-43-4
CS-0005486
Methyl 4-(methyloxy)-2-pyridinecarboxylate
2-Pyridinecarboxylic acid, 4-methoxy-, methyl ester

MDL Number

MFCD00956223

FAQ

What are the physical and chemical properties of Methyl 4-methoxy-2-pyridinecarboxylate (CAS: 29681-43-4)?

Methyl 4-methoxy-2-pyridinecarboxylate (CAS: 29681-43-4) is a colorless to light yellow liquid. It has a molecular weight of 188.19 g/mol and a density of approximately 1.1 g/cm³. The compound is soluble in common solvents like ethanol and acetone but has low solubility in water. It is relatively stable but can react with strong bases. Its reactivity mainly includes nucleophilic substitution and ester hydrolysis.

How is Methyl 4-methoxy-2-pyridinecarboxylate (CAS: 29681-43-4) typically synthesized?

Methyl 4-methoxy-2-pyridinecarboxylate (CAS: 29681-43-4) is typically synthesized via the esterification of 4-methoxy-2-pyridinecarboxylic acid with methanol in the presence of a sulfuric acid catalyst. The reaction is carried out at room temperature, and the yield is around 85%. The product is then purified by recrystallization or column chromatography.

What industries use Methyl 4-methoxy-2-pyridinecarboxylate (CAS: 29681-43-4)?

Methyl 4-methoxy-2-pyridinecarboxylate (CAS: 29681-43-4) is used in various industries, particularly in the pharmaceutical sector for the synthesis of certain compounds. It is also used in the polymer industry for modifying the properties of polymers and in electronic applications for sensor components and semiconductor materials.

What precautions should be taken when handling Methyl 4-methoxy-2-pyridinecarboxylate (CAS: 29681-43-4)?

When handling Methyl 4-methoxy-2-pyridinecarboxylate (CAS: 29681-43-4), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a cool, dry place, away from direct sunlight and heat sources. Spills should be handled carefully, and proper disposal methods should be followed. Always refer to the safety data sheet (SDS) for detailed information on handling and emergency response.