6-Monoamino-b-cyclodextrin

Basic Information

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CAS Number

29390-67-8

Molecular Formula

C42H71NO34

Molecular Weight

1134 g/mol

EINECS

1312995-182-4

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

White to off-white

Melting Point

203 °C (decomp)

Boiling Point

1527.8±60.0 °C(Predicted)

Density

1.608±0.06 g/cm3(Predicted)

Solubility

Soluble in water, DMF, DMSO.Insoluble in acetone, methanol, chloroform.

SMILES

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O1[C@]2([H])[C@@]([H])([C@]([H])([C@@]([H])([C@@]([H])(C([H])([H])O[H])O2)O[C@]2([H])[C@@]([H])([C@]([H])([C@@]([H])([C@@]([H])(C([H])([H])O[H])O2)O[C@@]2([H])[C@]([H])([C@@]([H])([C@]([H])([C@]([H])(C([H])([H])O[H])O2)O[C@@]2([H])[C@]([H])([C@@]([H])([C@]([H])([C@]([H])(C([H])([H])O[H])O2)O[C@@]2([H])[C@]([H])([C@@]([H])([C@]([H])([C@]([H])(C([H])([H])O[H])O2)O[C@@]2([H])[C@]([H])([C@@]([H])([C@]([H])([C@]([H])(C([H])([H])O[H])O2)O[C@]2([H])[C@@]([H])([C@]([H])([C@@]1([H])[C@@]([H])(C([H])([H])N([H])[H])O2)O[H])O[H])O[H])O[H])O[H])O[H])O[H])O[H])O[H])O[H])O[H])O[H])O[H])O[H]

InChI

1S/C42H71NO34/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-42,44-63H,1-7,43H2/t8-,9+,10-,11+,12-,13+,14+,15-,16-,17+,18-,19+,20+,21+,22-,23-,24+,25-,26+,27+,28+,29-,30+,31-,32+,33-,34+,35+,36-,37-,38+,39-,40+,41+,42+/m1/s1

InChIKey

OZBFLQITCMCIOY-DPWLHOGPSA-N

LogP

-15.264200000000029

pKa

12.57±0.70(Predicted)

Topological Polar Surface Area

559.8400000000001 Å²

Hydrogen Bond Donor/Acceptor

22 / 35

Complexity

1840

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Stability

Hygroscopic

Synonyms & References

English

6(I)-amino-6(I)-deoxycyclomaltoheptaose
6-Monodeoxy-6-monoamino-beta-cyclodextrine
Mono-6-Amino-6-deoxy-beta-Cyclodextrin
6-AMino-6-deoxy -cyclodextrin
mono-6-amino-mono-6-deoxy-β-CD
Mono-(6-amino-6-deoxy)-β-cyclodextrin
Mono-(6-amino-6-deoxy)-2-cyclodextrin
6-Monodeoxy-6-MonoaMino-β-cyclodextrine
b-Cyclodextrin, 6A-amino-6A-deoxy-
6-Amino-6-deoxycyclomaltoheptaose
6-Deoxy-6-amino-beta-cyclodextrin
6-Monoamino-6-monodeoxy-beta-cyclodextrin
6-Monoamino-beta-cyclodextrin
6-Monodeoxy-6-monoamino-beta-cyclodextrin
Mono(6-amino-6-deoxy)-beta-cyclodextrin
CID 134691995

MDL Number

MFCD03452964

EC Number

1312995-182-4

Customs Code

9999999999

FAQ

What is 6-Monoamino-β-cyclodextrin (CAS: 29390-67-8)?

6-Monoamino-β-cyclodextrin (CAS: 29390-67-8) is a type of hydroxyalkylated cyclodextrin, a modified form of β-cyclodextrin with one amino group attached at the C6 position. It is water-soluble and has a cylindrical shape with a hydrophobic cavity and hydrophilic exterior, making it useful for encapsulating hydrophobic compounds.

What are the main uses of 6-Monoamino-β-cyclodextrin (CAS: 29390-67-8)?

6-Monoamino-β-cyclodextrin (CAS: 29390-67-8) is widely used in pharmaceuticals for drug delivery, stabilizing proteins, and enhancing drug solubility. It is also used in food applications for flavor encapsulation and in research for various analytical procedures due to its unique properties.

Is 6-Monoamino-β-cyclodextrin (CAS: 29390-67-8) safe?

6-Monoamino-β-cyclodextrin (CAS: 29390-67-8) is considered safe for most applications. However, it should be handled with care due to its potential for skin irritation. Protective gloves and goggles are recommended during handling. It is non-toxic and non-carcinogenic.

How should 6-Monoamino-β-cyclodextrin (CAS: 29390-67-8) be stored?

6-Monoamino-β-cyclodextrin (CAS: 29390-67-8) should be stored in a tightly sealed container at room temperature (15-25°C) and protected from moisture and light. Avoid storing near heat sources or in humid environments to maintain its stability and efficacy.